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Safety and Pharmacokinetics Study of Naldemedine in Paediatric Participants Receiving Opioids

NCT05588323

The primary objective of this study is to evaluate the pharmacokinetic (PK) profile of naldemedine and nor-naldemedine after a single oral dose of naldemedine in pediatric participants who are receiving or about to receive opioids.

Opioid-Induced Constipation (OIC)

Shionogi24 participantsStarted Jan 2023

Tirana, Albania • Yerevan, Armenia • Brussels, Belgium +13 more locations

COMPLETEDPhase 2

A Study to Assess the Safety, Tolerability and Clinical Activity of TD-1211 in Patients With Opioid-Induced Constipation

NCT01333540

A dose-escalation study to assess the safety, tolerability and clinical activity of TD-1211 in patients with opioid-induced constipation.

Opioid-induced Constipation (OIC)

Theravance Biopharma69 participantsStarted May 2011

Salt Lake City, Utah, United States

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Safety and Pharmacokinetics Study of Naldemedine in Paediatric Participants Receiving Opioids

A Study to Assess the Safety, Tolerability and Clinical Activity of TD-1211 in Patients With Opioid-Induced Constipation

Safety and Pharmacokinetics Study of Naldemedine in Paediatric Participants Receiving Opioids

A Study to Assess the Safety, Tolerability and Clinical Activity of TD-1211 in Patients With Opioid-Induced Constipation