Effects of Laser Therapy and Vitamin D Pills on Braces Tooth Movement: A Random Controlled Study

NCT07286474

This clinical trial aims to evaluate the efficacy of low-level laser therapy (LLLT) in conjunction with oral vitamin D3 supplementation in accelerating orthodontic tooth movement in adults with crowded mandibular anterior teeth undergoing orthodontic treatment. Additionally, the study seeks to assess the safety profile and potential adverse effects, including pain and root resorption. The primary research questions are as follows: 1. Does vitamin D3 enhance the rate of orthodontic tooth movement? 2. Does the combination of vitamin D3 and LLLT result in a greater acceleration of tooth movement compared to either intervention alone? 3. Do vitamin D3 and LLLT influence the extent of root resorption? 4. Do vitamin D3 and LLLT mitigate pain associated with orthodontic treatment? 5. Do vitamin D3 and LLLT reduce the frequency of required clinical visits? The study will compare the outcomes of orthodontic treatment with braces alone, braces with vitamin D3 supplementation, and braces with both vitamin D3 and LLLT, to determine their effects on the rate of tooth movement, pain reduction, and root resorption. Participants will undergo the following procedures: * A blood test to assess baseline vitamin D levels. * Placement of orthodontic braces. * Daily administration of vitamin D3 supplements for those assigned to the relevant groups, commencing with a loading dose one week prior to the initiation of orthodontic treatment. * Application of LLLT to the gingival tissues for participants in the corresponding group, administered at the start and during follow-up visits. * Regular clinic visits every four weeks for monitoring, pain assessment, and measurement of tooth movement until the completion of orthodontic alignment.