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Extracorporeal Therapy and Therapeutic Drug Monitoring

NCT07287813

The aim of this study is to comparatively evaluate serum concentrations of continuously applied antibiotics in ICU patients, with and without ECMO/RRT support.

ICU Patients With ECMO And-or RRT and With Gram Negative Infections Susceptible to BL-BLIs

Fondazione IRCCS Policlinico San Matteo di Pavia40 participantsStarted Dec 2025

Pavia, Lombardy, Italy

RECRUITING

PK/PD Relationship of CAZ/AVI and FOS in the Treatment of Patients With Infections Due to CRE

NCT06717594

A multicenter international prospective observational pharmacological study in adult patients (≥18 years) treated with ceftazidime/avibactam (CAZ/AVI) alone or with CAZ/AVI plus fosfomycin (FOS) for infection due to carbapenem-resistant Enterobacterales (CRE) (KPC and/or OXA-48).

Gram Negative InfectionsAntimicrobial Resistance (AMR)

IRCCS Azienda Ospedaliero-Universitaria di Bologna60 participantsStarted Dec 2023

Bologna, Bologna, Italy • Seville, Seville, Spain

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Extracorporeal Therapy and Therapeutic Drug Monitoring

PK/PD Relationship of CAZ/AVI and FOS in the Treatment of Patients With Infections Due to CRE

Extracorporeal Therapy and Therapeutic Drug Monitoring

PK/PD Relationship of CAZ/AVI and FOS in the Treatment of Patients With Infections Due to CRE