Clinical Trials in Texas

Showing 2081-2100 of 7,265 trials

A Study to Assess the Efficacy, Safety, and Tolerability of KPL-716 in Reducing Pruritus in Chronic Pruritic Diseases

NCT03858634

Participants with diseases characterized by chronic pruritus experiencing moderate to severe pruritus will be enrolled in this pilot Phase 2 study. The diseases characterized by chronic pruritus investigated in this pilot study currently include chronic idiopathic urticaria (CIU), chronic idiopathic pruritus (CIP), lichen planus (LP), lichen simplex chronicus (LSC) and plaque psoriasis (PPs).

Chronic Idiopathic UrticariaChronic Idiopathic PruritusLichen Planus+2 more

Genentech, Inc.58 participantsStarted May 2019

Anniston, Alabama, United States • Phoenix, Arizona, United States • Hot Springs, Arkansas, United States +11 more locations

TERMINATEDPhase 155 miles

Study of MK-6552 in Participants With Narcolepsy Type 1 (MK-6552-004)

NCT06179407

The purpose of this study is to evaluate the safety, efficacy, pharmacokinetics (PK), and pharmacodynamics (PD) of MK-6552 in participants with Narcolepsy Type 1 (NT1). Part 1 will evaluate safety, tolerability, and PK of MK-6552 after administration of ascending doses in a single day to support a dose level decision for Part 2. Part 2 will investigate the PD of MK-6552 after single-day and multiple-day administration. Participants who complete Part 1 and demonstrate that they are able to tolerate at least one dose level of MK-6552 will participate in Part 2.

Narcolepsy

Merck Sharp & Dohme LLC9 participantsStarted Jan 2024

Colorado Springs, Colorado, United States • Brandon, Florida, United States • Atlanta, Georgia, United States +2 more locations

A Study to Assess the Efficacy, Safety, and Tolerability of KPL-716 in Reducing Pruritus in Chronic Pruritic Diseases

Study of MK-6552 in Participants With Narcolepsy Type 1 (MK-6552-004)

Find Trials by Condition in Texas

Safety and Immunogenicity of Quadrivalent Influenza mRNA Vaccine MRT5410 in Adult Participants 18 Years of Age and Older

ALTTO (Adjuvant Lapatinib And/Or Trastuzumab Treatment Optimisation) Study; BIG 2-06/N063D

A Clinical Effectiveness Study Examining the Efficacy and Safety of ONS-5010 in Subjects With Neovascular Age-related Macular Degeneration (AMD)

Identifying Predictors of Poor Health-Related Quality-of-Life Among Pediatric Hematopoietic Stem Cell Donors

A Phase 1/2 Study of VIO-01 in Participants With Recurrent Solid Tumors

PF-06863135 As Single Agent And In Combination With Immunomodulatory Agents In Relapse/Refractory Multiple Myeloma

A Study to Evaluate the Efficacy and Safety of Sutetinib Maleate Capsule in Locally Advanced or Metastatic NSCLC

Patient Reported Outcomes With WaveLight LASIK

Safety, PK, PD, Clinical Activity of KT-333 in Adult Patients With Refractory Lymphoma, Large Granular Lymphocytic Leukemia, Solid Tumors

A Study of Mavacamten in Participants With HFpEF and Elevation of NT-proBNP With or Without Elevation of cTnT

NOVOCART®3D for Treatment of Articular Cartilage of the Knee

EVAS2 IDE Prospective, Multicenter, Single Arm Safety and Effectiveness Confirmatory Study

A Study of LY3561774 in Participants With Mixed Dyslipidemia

BIOTRONIK Conduction System Pacing With the Solia Lead

Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer

Can Intraosseous Antibiotics Improve the Results of Irrigation & Debridement and Prosthetic Retention for PJI?

A Study to Compare How the Study Medicine (PF-07923568) is Processed in Participants With Different Levels of Loss of Liver Function to Healthy Participants.

A Study of JR-171 in Patients With Mucopolysaccharidosis I