Clinical Trials in Tennessee

Showing 1961-1980 of 9,675 trials

OCS DCD Heart + CAP Continued Follow-Up

NCT05741723

The objective of this post-approval study is to evaluate long-term outcomes of patients enrolled in the OCS DCD Heart and OCS DCD Heart CAP studies.

Heart Transplant

TransMedics276 participantsStarted Nov 2019

La Jolla, California, United States • Palo Alto, California, United States • New Haven, Connecticut, United States +17 more locations

RECRUITINGPhase 129 miles

First-in-Human Study of OKI-219 in Advanced Solid Tumors and Advanced Breast Cancer

NCT06239467

OKI-219-101 is a Phase 1a/1b, open-label, multicenter, dose-escalation study designed to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PDx), and efficacy of OKI-219 as monotherapy and in combination with other anti-cancer drugs. Phase 1a (Part A) will investigate escalating doses of OKI-219 monotherapy, and Phase 1b will investigate OKI-219 (at a tolerated dose determined in Part A) in combination with fulvestrant (Part B), trastuzumab and tucatinib (Part C), atirmociclib (Part D), and ribociclib and fulvestrant (Part E). Participants will continue to receive study treatment until disease progression, intolerable toxicity, or other study treatment withdrawal criteria are met.

Advanced CancerBreast CancerAdvanced Solid Tumors+1 more

OnKure, Inc.200 participantsStarted Feb 2024

Encinitas, California, United States • La Jolla, California, United States • Los Angeles, California, United States +31 more locations

OCS DCD Heart + CAP Continued Follow-Up

First-in-Human Study of OKI-219 in Advanced Solid Tumors and Advanced Breast Cancer

Find Trials by Condition in Tennessee

Neoadjuvant Neratinib in Stage I-III HER2-Mutated Lobular Breast Cancers

A Study of Nemtabrutinib (MK-1026) in Participants With Relapsed or Refractory Hematologic Malignancies (ARQ 531-101/MK-1026-001)

S1702 Isatuximab in Treating Patients With Relapsed or Refractory Primary Amyloidosis

Nivolumab in Treating Patients With Persistent, Recurrent, or Metastatic Cervical Cancer

A Trial of Centanafadine Efficacy, Safety, and Tolerability in Adult Subjects With Binge Eating Disorder

A Study of Relatlimab Plus Nivolumab Versus Nivolumab Alone in Participants With Advanced Melanoma

Examining Distinct Immunophenotypes to Validate and Enhance Rational Treatment in Systemic Lupus

A Prospective, US-based Study Assessing Mogamulizumab-associated Rash in Patients Diagnosed With Mycosis Fungoides or Sezary Syndrome and Treated With Standard of Care Mogamulizumab

Safety of Simultaneous mRNA COVID-19 Vaccine With Other Childhood Vaccines in Young Children

Gla-300 and IDeg-100 in Insulin-Naïve People With Type 2 Diabetes Mellitus and Renal Impairment

A Study of LM-24C5 For Advanced Solid Tumors

FebriDx® Method Comparison Study Protocol

ACHIEVE Hearing Intervention Follow-Up Study

A Phase I/II Study of Hypofractionated Proton Therapy for Stage II-III Non-Small Cell Lung Cancer

Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer

Efficacy and Safety of Tolebrutinib (SAR442168) Tablets in Adult Participants With Generalized Myasthenia Gravis

Safety, Usability, and Effectiveness of a Gait Exoskeleton for Children and Adolescents With Neurodevelopmental Disorders.

Skin Reactions Related to Thoracic Implantable Chamber Dressings