Clinical Trials in Tennessee

Showing 12701-12720 of 17,345 trials

A Study of MM-111 and Paclitaxel With Trastuzumab in Patients HER2 Positive Carcinomas of the Distal Esophagus, Gastroesophageal (GE) Junction and Stomach

NCT01774851

To determine whether the combination of MM-111 plus paclitaxel and trastuzumab is more effective than paclitaxel and trastuzumab alone

HER-2 Gene AmplificationEsophagus CancerGastroesophageal Junction Cancer+1 more

Merrimack Pharmaceuticals84 participantsStarted Jan 2013

Birmingham, Alabama, United States • Los Angeles, California, United States • Los Angeles, California, United States +18 more locations

TERMINATEDPhase 229 miles

Chemo/XRT +/- Amifostine to Assess Outcomes Related to Xerostomia, Mucositis, & Dysphagia

NCT00503776

RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Amifostine may decrease the side effects caused by chemotherapy and radiation therapy. It is not yet known whether chemotherapy and radiation therapy are more effective with or without amifostine in treating head and neck cancer. PURPOSE: This randomized phase II trial is studying amifostine to see how well it works compared with standard care in reducing side effects in patients undergoing chemotherapy and radiation therapy for stage III or stage IV head and neck cancer.

DysphagiaHead and Neck CancerMucositis+1 more

Vanderbilt-Ingram Cancer Center41 participantsStarted Jan 2006

Nashville, Tennessee, United States

A Study of MM-111 and Paclitaxel With Trastuzumab in Patients HER2 Positive Carcinomas of the Distal Esophagus, Gastroesophageal (GE) Junction and Stomach

Chemo/XRT +/- Amifostine to Assess Outcomes Related to Xerostomia, Mucositis, & Dysphagia

Find Trials by Condition in Tennessee

Effect of Valproic Acid Concentration on Photic Response

This Was an Open-label, Single-arm Extension Study (CFTY720D2306E1) to a Double-blind, Randomized Multicenter, Placebo-controlled, Parallel-group Core Study (CFTY720D2306) in PPMS.

To Evaluate Sarilumab - SAR153191 (REGN88) - Auto-injector Device In Patients With Rheumatoid Arthritis

Trial of Linaclotide in Patients With Chronic Idiopathic Constipation

To Evaluate the Immunogenicity and Safety of Sarilumab Administered as Monotherapy in Patients With Rheumatoid Arthritis (RA)

A 48 Week Study Comparing Treatment With Saquinavir + Lopinavir/Ritonavir in Combination With Enfuvirtide HAART Versus Saquinavir + Lopinavir/Ritonavir + Other Nucleoside Combinations to See the Efficacy of These Treatments in Patients Infected With HIV-1

Stem Cell Related Donor Safety Study

Literacy-Adapted Psychosocial Treatments for Chronic Pain --- "Learning About Mastering/My Pain"

Inhaled Corticosteroid Replacement Study - Efficacy and Safety of Ro 27-2441 (Test Drug) in Moderate Persistent Asthma

A Study of Intravenous Thrombolysis With Alteplase in MRI-Selected Patients

Safety and Efficacy of Topical Thrombin (Human) Grifols as an Adjunct to Hemostasis During Surgery

Impact of SBI, a Medical Food, on Nutritional Status in Patients With HIV-associated Enteropathy

Hyper- and Hypokalemic Periodic Paralysis Study

Evaluation of Immediate Versus Delayed Loading of Dental Implants With a Modified Surface

Phase II Study to Analyze Sarilumab in Non-Infectious Uveitis

A Study To Evaluate The Safety Of Voriconazole As Treatment Of Invasive Aspergillosis (Fungal Infection) And Other Rare Molds In Children

Evaluating Processes of Care & the Outcomes of Children in Hospital (EPOCH)

SOD1 Inhibition by Pyrimethamine in Familial Amyotrophic Lateral Sclerosis (ALS)