Clinical Trials in Tennessee

Showing 7261-7280 of 15,329 trials

New Formulations of Propafenone to Treat Atrial Fibrillation

NCT02710669

Propafenone is a currently used medicine to treat atrial fibrillation and is a mixture of two compounds, (R)-propafenone and (S)-propafenone. In this study, the investigators will randomize participants to (R)-propafenone, (S)-propafenone, or placebo.

Atrial Fibrillation

Vanderbilt University193 participantsStarted Oct 2016

Nashville, Tennessee, United States

COMPLETEDPhase 229 miles

PDE5 Inhibition for Obesity-Related Cardiometabolic Dysfunction

NCT02819440

Obesity and its adverse cardiometabolic consequences are major public health problems. Several features of obesity contribute to the associated cardiovascular risk and are potential targets for intervention. These include insulin resistance and beta cell dysfunction, reduced metabolic rate, and impaired aerobic capacity.The purpose of this study is to examine if the phosphodiesterase type 5A inhibitor tadalafil improves cardiometabolic health in individuals who are obese and insulin resistant.

HealthyObese

Vanderbilt University Medical Center141 participantsStarted Jul 2016

Nashville, Tennessee, United States

COMPLETEDPhase 229 miles

Safety and Immunogenicity of the RSV-F Vaccine in Older Adults Previously Treated With the Same Vaccine or Placebo in the Prior Year.

NCT02593071

This study will enroll subjects who received the RSV F vaccine or placebo in the earlier study (RSV-E-201, Year 1) and re-randomize them to receive either vaccine or placebo in a second season. This design will permit evaluation of the safety and immunogenicity of revaccination in a second RSV season, and the safety and immunogenicity of revaccination over two years.

Respiratory Syncytial Virus (RSV)

Novavax1,330 participantsStarted Oct 2015

Redding, California, United States • Stockbridge, Georgia, United States • Lenexa, Kansas, United States +7 more locations

New Formulations of Propafenone to Treat Atrial Fibrillation

PDE5 Inhibition for Obesity-Related Cardiometabolic Dysfunction

Safety and Immunogenicity of the RSV-F Vaccine in Older Adults Previously Treated With the Same Vaccine or Placebo in the Prior Year.

Find Trials by Condition in Tennessee

Study of the Safety and Efficacy of Elagolix in Women With Polycystic Ovary Syndrome

Radiation Therapy in Treating Patients With Prostate Cancer

A Multicenter Observational Study to Evaluate the Effectiveness of Patisiran in Patients With Polyneuropathy of ATTRv Amyloidosis With a V122I or T60A Mutation

ARDA Software for the Detection of mtmDR

PDR001 Plus LAG525 for Patients With Advanced Solid and Hematologic Malignancies

Percutaneous Endovascular Aneurysm Repair (PEVAR) Trial

Pazopanib Hydrochloride and Topotecan Hydrochloride in Treating Patients With Metastatic Soft Tissue and Bone Sarcomas

A Study of LJPC-401 for the Treatment of Iron Overload in Adult Patients With Hereditary Hemochromatosis

A Study to Assess the PK and Pharmacodynamics of IPX203 in Subjects With Advanced Parkinson's Disease

A Study of Granexin® Gel for the Reduction of Scar Formation in Surgical Wounds Following Bilateral Anchor Incision Breast Surgery

Evaluation of Upper GI Ulceration Induced by PL2200 Versus Aspirin in At-Risk Subjects

Triton Reference Database

An Evaluation of the Clinical Utility and Safety of the Visant Medical Canalicular Plug

RSV F Vaccine Maternal Immunization Study in Healthy Third-trimester Pregnant Women.

Evaluation of EpiBone-CMF for Mandibular Ramus Reconstruction

Aspirin and Zileuton and Biomarker Expression in Nasal Tissue of Current Smokers

Ahmed Glaucoma Valve Surgery With Mitomycin-C