Clinical Trials in Tennessee

Showing 6141-6160 of 20,239 trials

Advocating for Supports to Improve Service Transitions

NCT04173663

This is a randomized intervention study to develop and test the national curriculum of a parent intervention training targeting parent's ability for advocate for services to improve the transition to adulthood for their youth with autism spectrum disorder (ASD). UPDATE regarding COVID-19: Due to social distancing restrictions, the in-person intervention series that began in Winter 2020 was paused in Spring 2020 for Cohort 1 intervention groups (TN and IL). The series resumed in Summer 2020 via synchronous web-conferencing. In response to continued pandemic regulations, ASSIST was permanently moved to synchronous web-conferencing in Fall 2020, and this method was the mode of delivery for all remaining sessions and series at all sites (TN, IL, WI). The remaining baseline data was also moved to remote collection through online interview and questionnaires in Spring 2020. The data collection for all follow ups and check ins (6, 12, 18, 24, and 30 month) were completed through web conference and/or phone calls in addition to online surveys. The final data collection for experimental and control groups from all sites will be complete by Summer 2023.

Autism Spectrum DisorderAutism

Vanderbilt University Medical Center185 participantsStarted Jan 2020

Chicago, Illinois, United States • Nashville, Tennessee, United States • Madison, Wisconsin, United States

Active Not RecruitingPhase 329 miles

HERTHENA-Lung02: A Study of Patritumab Deruxtecan Versus Platinum-based Chemotherapy in Metastatic or Locally Advanced EGFRm NSCLC After Failure of EGFR TKI Therapy

NCT05338970

Disease progression is typical for patients with epidermal growth factor receptor mutated (EGFRm) non-small cell lung cancer (NSCLC). Standard platinum-based chemotherapy offers limited efficacy and an unfavorable safety profile.There is an urgent need for more effective and tolerable therapies for patients with EGFRm NSCLC who have exhausted available targeted therapies. Clinical evidence suggest that patritumab deruxtecan constitutes a promising investigational therapy for patients with EGFRm NSCLC.

Nonsquamous Non-small Cell Lung CancerEGFR L858REGFR Exon 19 Deletion

Daiichi Sankyo586 participantsStarted Jul 2022

Anchorage, Alaska, United States • Springdale, Arkansas, United States • Duarte, California, United States +179 more locations

Advocating for Supports to Improve Service Transitions

HERTHENA-Lung02: A Study of Patritumab Deruxtecan Versus Platinum-based Chemotherapy in Metastatic or Locally Advanced EGFRm NSCLC After Failure of EGFR TKI Therapy

Find Trials by Condition in Tennessee

Autonomic Determinants of POTS - Pilot 2

Nirogacestat for Adults With Desmoid Tumor/Aggressive Fibromatosis (DT/AF)

A Study of BTX-A51 in People With Advanced Solid Tumor and Breast Cancer

Avelumab in First-line NSCLC (JAVELIN Lung 100)

Study of the Safety, Tolerability, Pharmacokinetics and Biomarker of DONQ52 in Celiac Disease Patients

A Study to Assess the Validation and Mapping of the Suicide Ideation and Behavior Assessment

An Observational Study of Beta-Blocker Use in Patients With COPD and Acute MI

Extended Access Program With Lorcaserin For The Treatment of Dravet Syndrome and Other Refractory Epilepsies

Phase 1, Open-label, Single Dose Study to Examine Safety, Tolerability, Pharmacokinetics and Virologic Impact of VRC01LS or VRC07-523LS in HIV-infected Viremic Adults

A Study to Evaluate the Pharmacokinetics of JNJ-56021927 in Participants With Mild or Moderate Hepatic Impairment Compared With Participants With Normal Hepatic Function

Early Feasibility Evaluation of the AccuCinch® Ventricular Restoration System in Patients With Heart Failure and Reduced Ejection Fraction

A Study of Loncastuximab Tesirine and Rituximab (Lonca-R) in Previously Untreated Unfit/Frail Participants With Diffuse Large B-cell Lymphoma (DLBCL)

D-CARE - The Dementia Care Study: A Pragmatic Clinical Trial of Health System-Based Versus Community-Based Dementia Care

Pulmonary Rehabilitation Before Lung Cancer Resection

Phase 2 Platform Study in Patients With Advanced Non-Small Lung Cancer Who Progressed on First-Line Osimertinib Therapy (ORCHARD)

Establishing Efficacy of an Inpatient Intervention and Phone App to Reduce Suicidal Risk

Bright Ideas - CIN Feasibility Study

A Randomized Controlled Trial of TNK-tPA Versus Standard of Care for Minor Ischemic Stroke With Proven Occlusion