Clinical Trials in Tennessee

Showing 5661-5680 of 20,239 trials

Dose Escalation of RMC-5552 Monotherapy in Relapsed/Refractory Solid Tumors

NCT04774952

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetic (PK), and pharmacodynamic (PD) profiles of escalating doses of RMC-5552 monotherapy in adult participants with relapsed/refractory solid tumors and to identify the recommended Phase 2 dose (RP2D).

Solid Tumors

Revolution Medicines, Inc.58 participantsStarted Apr 2021

Irvine, California, United States • Sacramento, California, United States • San Francisco, California, United States +5 more locations

COMPLETEDNA29 miles

Conduction System Pacing Optimized Therapy

NCT04905290

The purpose of the CSPOT study is to determine the best mode of cardiac resynchronization therapy (CRT) pacing for different populations of CRT patients, comparing traditional biventricular or left ventricular pacing (BiV), conduction system pacing (CSP)-only, and conduction system pacing optimized therapy (CSPOT) also known as a combination of conduction system pacing (CSP) and left ventricular (LV) pacing. Additionally, safety of the system will be assessed.

Heart Failure

Medtronic Cardiac Rhythm and Heart Failure60 participantsStarted Nov 2021

Tampa, Florida, United States • Chicago, Illinois, United States • Houma, Louisiana, United States +9 more locations

Dose Escalation of RMC-5552 Monotherapy in Relapsed/Refractory Solid Tumors

Conduction System Pacing Optimized Therapy

Find Trials by Condition in Tennessee

Ureteral Stent Placement After Ureteroscopy for Renal Stones: A Randomized Controlled Trial

Safety Study of AG-120 or AG-221 in Combination With Induction and Consolidation Therapy in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) With an IDH1 and/or IDH2 Mutation

Study of Efficacy, Safety and Tolerability of CMK389 in Patients With Chronic Pulmonary Sarcoidosis

Pevonedistat, Azacitidine, Fludarabine Phosphate, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

A Study of Pazopanib With or Without Abexinostat in Patients With Locally Advanced or Metastatic Renal Cell Carcinoma (RENAVIV)

Prediction by Ultrasound of the Risk of Hepatic Cirrhosis in Cystic Fibrosis

MRI to Characterize and Predict CF Liver Disease in PUSH Cohort

R3 Delta Ceramic Acetabular System PAS U.S.

Tritanium® Primary Acetabular Shell Study

Metformin Hydrochloride in Preventing Breast Cancer in Patients With Atypical Hyperplasia or In Situ Breast Cancer

FlowMet-R Blood Flow Measurement for the Diagnosis of Peripheral Artery Disease and Critical Limb Ischemia

An 8-week Open-label Study of an Accelerated and Slower Switching to Xanomeline/Trospium Following Atypical Antipsychotic Treatment in Participants With Schizophrenia

Filgrastim-Mobilized Stem Cells for Transplantation Using Unrelated Donors

Safety and Tolerability of BION-1301 in Healthy Volunteers and Adults With IgA Nephropathy (IgAN)

The GORE VBX FORWARD Clinical Study: A Comparison of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis to Bare Metal Stenting for Patients With Complex Iliac Occlusive Disease

BAsel Syncope EvaLuation (BASEL IX) Study

Leading in MPNs Beyond Ruxolitinib in Combo With T-Regs

LITMUS Imaging Study