Clinical Trials in Tennessee

Showing 5101-5120 of 20,239 trials

ACE2016 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors Expressing Epidermal Growth Factor Receptor (EGFR)

NCT06415487

ACE2016 is an off-the-shelf, allogeneic gamma delta T (gdT) cell therapy derived from healthy donors, that is under investigation for the treatment of Locally Advanced or Metastatic Solid Tumors Expressing Epidermal Growth Factor Receptor (EGFR). The ACE2016-001 study is an open-label, Phase I, first-in-human (FIH) study that aims to evaluate the safety and tolerability, persistency, pharmacodynamics and efficacy of ACE2016 in patients with Locally Advanced or Metastatic Solid Tumors Expressing Epidermal Growth Factor Receptor (EGFR).

Locally Advanced Solid TumorMetastatic Solid Tumor

Acepodia Biotech, Inc.30 participantsStarted Aug 2024

San Diego, California, United States • Denver, Colorado, United States • Nashville, Tennessee, United States +6 more locations

Active Not RecruitingPhase 229 miles

Pertuzumab and Trastuzumab as Neoadjuvant Treatment in Patients With HER2-Positive Breast Cancer

NCT01937117

This research is being done to determine if early changes on a type of imaging procedure called PET (Positron Emission Tomography) can predict which patients are most likely to respond to the combination of trastuzumab and pertuzumab when given prior to surgery.

Breast Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins88 participantsStarted Jan 2014

Birmingham, Alabama, United States • Washington D.C., District of Columbia, United States • Indianapolis, Indiana, United States +7 more locations

ACE2016 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors Expressing Epidermal Growth Factor Receptor (EGFR)

Pertuzumab and Trastuzumab as Neoadjuvant Treatment in Patients With HER2-Positive Breast Cancer

Find Trials by Condition in Tennessee

A Study to Investigate LYL797 in Adults With Solid Tumors

Utility of PCD Diagnostics to Improve Clinical Care

Project PAIR: Parent-implemented Articulation Intervention With Recast

Safety, Tolerability & Potential Anti-cancer Activity of Increasing Doses of AZD5363 in Different Treatment Schedules

A Depression and Opioid Pragmatic Trial in Pharmacogenetics (Depression Trial)

Blood and Stool Sample Collection in Subjects With a Diagnosis of Colorectal Cancer or Colorectal Lesion: Act Fast

24 Weeks Double-blind Randomized Placebo-controlled Trial to Evaluate Efficacy, PK, Safety of LOU064 in Adolescents (12 - <18) With CSU and Inadequate Response to H1-antihistamine Followed by Optional 3 Years Open-label Extension and an Optional 3 Years Safety Long-term Treatment-free Follow-up

Study of Neoantigen-specific Adoptive T Cell Therapy for Newly Diagnosed MGMT Negative Glioblastoma Multiforme (GBM)

Distal Radius Interventions for Fracture Treatment

A Study to Investigate LYL845 in Adults With Solid Tumors

A Phase III Trial of With Marizomib in Patients With Newly Diagnosed Glioblastoma

A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic Lymphoma

Immune Checkpoint Inhibitor Nivolumab in People With Recurrent Select Rare CNS Cancers

Personalized AZithromycin/metronidAZole Therapy in Pediatric Crohn's Disease (CD)

A Study to Evaluate Guselkumab for the Treatment of Participants With New-onset or Relapsing Giant Cell Arteritis

Beacon Sensors and Telerehabilitation for Low Vision

Pragmatic Randomised Trial of High Or Standard PHosphAte Targets in End-stage Kidney Disease (PHOSPHATE)

Perioperative Therapy for Resectable and Borderline-Resectable Pancreatic Adenocarcinoma With Molecular Correlates