Clinical Trials in Tennessee

Showing 4501-4520 of 15,329 trials

LYT-200 Alone and in Combination With Chemotherapy or Tislelizumab in Patients With Locally Advanced or Metastatic Solid Tumors

NCT04666688

A Phase 1/2 Open-label, Multi-center Study of the Safety, Pharmacokinetics, and Anti-tumor Activity of LYT-200 Alone and in Combination with Chemotherapy or Tislelizumab in Patients with Metastatic Solid Tumors

Metastatic CancerSolid TumorPancreatic Cancer+3 more

PureTech44 participantsStarted Dec 2020

Los Angeles, California, United States • Denver, Colorado, United States • Denver, Colorado, United States +9 more locations

Active Not RecruitingPhase 1/229 miles

A Study of ERAS-007 in Patients With Advanced Gastrointestinal Malignancies

NCT05039177

* To evaluate the safety and tolerability of escalating doses of ERAS-007 in combination with other cancer therapies in study participants with advanced GI malignancies. * To determine the Maximum Tolerated Dose (MTD) and/or Recommended Dose (RD) of ERAS-007 administered in combination with other cancer therapies. * To evaluate the antitumor activity of ERAS-007 in combination with other cancer therapies. * To evaluate the PK profiles of ERAS-007 and other cancer therapies when administered in combination.

Metastatic Colorectal CancerMetastatic Pancreatic Ductal Adenocarcinoma

Erasca, Inc.102 participantsStarted Sep 2021

Birmingham, Alabama, United States • Duarte, California, United States • Orange, California, United States +11 more locations

LYT-200 Alone and in Combination With Chemotherapy or Tislelizumab in Patients With Locally Advanced or Metastatic Solid Tumors

A Study of ERAS-007 in Patients With Advanced Gastrointestinal Malignancies

Find Trials by Condition in Tennessee

Efficacy of Amicar for Children Having Craniofacial Surgery

A Clinical Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of PGDM1400LS Alone and in Combination With VRC07-523LS and PGT121.414.LS in Healthy, HIV-uninfected Adult Participants

A Trial of a Novel XPO1 Inhibitor in Participants With Advanced Solid Tumors

Open-Label Study of Setmelanotide in Hypothalamic Obesity

LDK378 Versus Chemotherapy in ALK Rearranged (ALK Positive) Patients Previously Treated With Chemotherapy (Platinum Doublet) and Crizotinib

A Study of the Safety and Tolerability in Participants With PIK3CA-related Overgrowth Spectrum or Proteus Syndrome Who Are Being Treated With Miransertib (MK-7075) in Other Studies (MK-7075-006)

Surveillance and Alert-based Multiparameter Monitoring to Reduce Worsening Heart Failure Events

A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Upadacitinib in Pediatric Participants With Severe Atopic Dermatitis

Study on BI 54903 (Inhaled Corticosteroid) Administered Twice Daily Via Respimat Inhaler in Patients With Asthma Inadequately Controlled on Medium Dose Inhaled Corticosteroid (ICS).

A Study of AK117 in Combination With Azacitidine in Patients With Myelodysplastic Syndromes

Selumetinib and Cyclosporine in Treating Patients With Advanced Solid Tumors or Advanced or Metastatic Colorectal Cancer

Artoss Prospective Spine Registry Outcomes

(Concerto) Study of BLU-451 in Advanced Cancers With EGFR Exon 20 Insertion Mutations

A Study of SGN-ALPV in Advanced Solid Tumors

Non-comparative Study of IFX-1 Alone or IFX-1+Pembrolizumab in Patients With Locally Advanced or Metastatic cSCC.

Psychological Response and Readiness Associated With OCD of the Knee

Clinical Trial to Assess Efficacy and Safety of the Human Anti-CD38 Antibody Felzartamab (MOR202) in IgA Nephropathy

Study of ExoFlo for the Treatment of Medically Refractory Crohn's Disease