Clinical Trials in Tennessee

Showing 3441-3460 of 20,239 trials

Neurophysiology Biomarkers of Cognitive Impairment Associated With Deep Brain Stimulation

NCT05933681

The study aims to investigate cognitive impairment associated with Deep Brain Stimulation (DBS) in Parkinson's Disease patients, with a focus on identifying neurophysiology biomarkers of DBS associated cognitive changes. Using neurophysiology data recorded during DBS surgeries and post-implantation, the research intends to identify biomarkers in order to optimize electrode placement, enhance programming, and ultimately minimize DBS-related cognitive side effects.

Parkinson Disease

Vanderbilt University Medical Center160 participantsStarted Jul 2023

Nashville, Tennessee, United States

TERMINATEDPhase 329 miles

Ganciclovir to Prevent Reactivation of Cytomegalovirus in Patients With Acute Respiratory Failure and Sepsis

NCT04706507

This is a phase 3 study designed to evaluate whether the administration of ganciclovir increases ventilator-free days in immunocompetent patients with sepsis associated acute respiratory failure. Our hypothesis is that IV ganciclovir administered early in critical illness will effectively suppress CMV reactivation in CMV seropositive adults with sepsis-associated acute respiratory failure thereby leading to improved clinical outcomes

Acute Respiratory Failure

Fred Hutchinson Cancer Center205 participantsStarted Jun 2021

Denver, Colorado, United States • Baltimore, Maryland, United States • Boston, Massachusetts, United States +17 more locations

Neurophysiology Biomarkers of Cognitive Impairment Associated With Deep Brain Stimulation

Ganciclovir to Prevent Reactivation of Cytomegalovirus in Patients With Acute Respiratory Failure and Sepsis

Find Trials by Condition in Tennessee

Study of Oral Food Challenge Biomarkers (SAFER)

A Research Study to Look at How Well CagriSema Helps People Living With Obesity Lose Weight and Maintain Weight Loss in the Long-term

A Study of Zigakibart in Adults With IgA Nephropathy

An Open-label, Single-arm Study to Evaluate Pharmacokinetics and Safety of Subcutaneous Sonelokimab in Adolescents With Moderate to Severe Hidradenitis Suppurativa (VELA-TEEN)

Open Label, Dose-finding, Pharmacokinetics, Safety and Tolerability Study of Oritavancin in Pediatric Participants With Suspected or Confirmed Bacterial Infections

UNITY VCS Vitreoretinal Surgery

Safely Optimizing Body Weight With TCMCB07 in Patients With Newly Diagnosed Metastatic Colorectal Cancer Undergoing Chemotherapy

A Research Study to Compare Two Semaglutide Medicines in People With Type 2 Diabetes

A Study of HBS-201 (Pitolisant Delayed-release)

A Trial to Evaluate the Efficacy and Safety of PQ912 in Patients With Early AD

A Study to Assess the Long-Term Safety and Efficacy of Donidalorsen in the Prophylactic Treatment of Hereditary Angioedema (HAE)

VIRTUUS Children's Study

Nirogacestat in Ovarian Granulosa Cell Tumors

Evaluation of OLX10212 in Patients With Neovascular Age-related Macular Degeneration

A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC in Adults With Ocular Myasthenia Gravis

A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Two Different Doses of Alpha1-Proteinase Inhibitor Subcutaneous (Human) 15% in Participants With Alpha1-Antitrypsin Deficiency

A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRX) Administered to Adults With Familial Chylomicronemia Syndrome (FCS) Previously Treated With Volanesorsen

A Study of the Genetic Basis of Response to Growth Hormone Treatment in Children With Idiopathic Short Stature