Clinical Trials in Tennessee

Showing 2461-2480 of 9,675 trials

A Study of the Drugs AGN-242428 and AGN-231868 in Participants With Dry Eye Disease

NCT04030962

This was a 2-stage study in which Stage 1 evaluated the safety of AGN-242428 and AGN-231868, how well they are tolerated, and how they move through the body when administered. After the sponsor's determination of adequate safety and tolerability of the interventions in Stage 1, Stage 2 began. Stage 2 also evaluated the safety and tolerability of AGN-242428 and AGN-231868, how effective they are in treating dry eye disease (DED), and assessed the plasma and tear exposure of both ophthalmic solutions.

Dry Eye DiseaseDry Eye Syndrome

AbbVie292 participantsStarted Mar 2020

Phoenix, Arizona, United States • Newport Beach, California, United States • Colorado Springs, Colorado, United States +8 more locations

Active Not RecruitingPhase 1/229 miles

Safety and Efficacy Study of CFI-402411 in Subjects With Advanced Solid Malignancies

NCT04521413

The purpose of this study is to test the safety of an investigational drug called CFI-402411 alone and in combination with pembrolizumab and to study its effects in patients with advanced solid tumors who have progressed following previous therapies.

Advanced Solid Malignancies

Treadwell Therapeutics, Inc170 participantsStarted Aug 2020

La Jolla, California, United States • Los Angeles, California, United States • New Haven, Connecticut, United States +10 more locations

A Study of the Drugs AGN-242428 and AGN-231868 in Participants With Dry Eye Disease

Safety and Efficacy Study of CFI-402411 in Subjects With Advanced Solid Malignancies

Find Trials by Condition in Tennessee

Parkinson's Foundation PD GENEration Genetic Registry

Non-Guided vs. Guided Surgery to Immediately Loaded PrimeTaper Implants in Partially Edentulous Patients

A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors

Study of Nalbuphine HCl ER Tablets in Hemodialysis Patients With Uremic Pruritus

Rucaparib in Treating Patients With Genomic LOH High and/or Deleterious BRCA1/2 Mutation Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)

Study to Assess the Immune Response, the Safety and the Reactogenicity of Respiratory Syncytial Virus (RSV) Prefusion Protein 3 Older Adult (OA) (RSVPreF3 OA) Investigational Vaccine When co Administered With PCV20 in Older Adults

Mycobacteriophage Treatment of Non-tuberculosis Mycobacteria

A Study to Learn About the Safety of BIIB080 Injections and Whether They Can Improve Symptoms of Participants With Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD Dementia Between 50 to 80 Years of Age

A Study of CFI-400945 With or Without Azacitidine in Patients With AML, MDS or CMML

Safety, Tolerability and Acceptability of Long-Acting Cabotegravir (CAB LA) for the Prevention of HIV Among Adolescent Males

Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)

StimRouter Registry Clinical Protocol

BCMA-directed CAR-T Cell Therapy in Adult Patients With Multiple Myeloma

A Phase 2 Study of the Safety and Efficacy of Brepocitinib in Adults With Cutaneous Sarcoidosis (BEACON)

PRimary Care Opioid Use Disorders Treatment (PROUD) Trial

Efficacy & Safety of rAd-IFN Administered With Celecoxib & Gemcitabine in Patients With Malignant Pleural Mesothelioma

Study of Safety, Tolerability and Efficacy of PBGM01 in Pediatric Participants With GM1 Gangliosidosis

Early Treatment of Language Impairment in Young Children With Autism Spectrum Disorder With Leucovorin Calcium