Clinical Trials in Seattle

Showing 901-920 of 4,491 trials

A Study of AC676 for the Treatment of Relapsed/Refractory B-Cell Malignancies

NCT05780034

This clinical trial is evaluating a drug called AC676 in participants with Relapsed/Refractory B-cell Malignancies. The main goals of the study are to: * Identify the recommended dose of AC676 that can be given safely to participants * Evaluate the safety profile of AC676 * Evaluate the pharmacokinetics of AC676 * Evaluate the effectiveness of AC676

Relapsed/Refractory B-cell Malignancies

Accutar Biotechnology Inc60 participantsStarted Jun 2023

Denver, Colorado, United States • Sarasota, Florida, United States • Chapel Hill, North Carolina, United States +6 more locations

RECRUITING< 1 mile

Multi-Center Molecular Diagnosis and Host Response of Respiratory Viral Infections in Pediatric Transplant Recipients

NCT05550298

The participants are being asked to take part in this clinical trial, a type of research study, because the participants are scheduled to receive or have recently received a hematopoietic cell transplant (HCT) or a solid organ transplant (SOT). Primary Objective To determine if pre-transplant screening for respiratory viral load predicts RVI within 1- year post-transplant among survivors. Secondary Objectives: * To develop and validate a classifier based on pre-transplant immunological profile predictive of developing an acute respiratory viral infection (aRVI), with RSV/PIV3/HMPV/SARS-CoV-2 through one-year post-transplant among survivors. * To develop and validate a classifier based on Day +100 post-transplant immunological profiles predictive of developing an acute respiratory viral infection (aRVI),with RSV/PIV3/HMPV/SARS-CoV-2 through one-year post-transplant among survivors .

Hematopoietic Cell TransplantSolid Organ TransplantRespiratory Viral Infection

Arkansas Children's Hospital Research Institute2,000 participantsStarted Dec 2022

Birmingham, Alabama, United States • Little Rock, Arkansas, United States • Washington D.C., District of Columbia, United States +24 more locations

A Study of AC676 for the Treatment of Relapsed/Refractory B-Cell Malignancies

Multi-Center Molecular Diagnosis and Host Response of Respiratory Viral Infections in Pediatric Transplant Recipients

Find Trials by Condition in Seattle

Selinexor (KPT-330) in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)

An Efficacy, Safety, and Tolerability Study of VRDN-003 in Participants With Active Thyroid Eye Disease (TED)

A Study of Recombinant AAV2/6 Human Factor 8 Gene Therapy SB-525 (PF-07055480) in Subjects With Severe Hemophilia A

Safety, Tolerability and Efficacy of AntiBKV as Treatment of BKV Infection in Kidney Transplant Recipients

Diagnosis and Treatment of CAD in Severe PAD After Lower Extremity Revascularization

Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission

A Study of Cabozantinib Compared With Placebo in Subjects With Radioiodine-refractory Differentiated Thyroid Cancer Who Have Progressed After Prior Vascular Endothelial Growth Factor Receptor (VEGFR) -Targeted Therapy

Self-Management Interventions After an ICD Shock

A Study to Assess Adverse Events of Fosigotifator (ABBV-CLS-7262) in Adults With Major Depressive Disorder

A Study Investigating the Efficacy and Safety of LBL-007 Plus Tislelizumab in Combination With Bevacizumab Plus Fluoropyrimidine Versus Bevacizumab Plus Fluoropyrimidine in Participants With Unresectable or Metastatic Colorectal Cancer

Evaluating Response to Vitamin D3 and K2 Supplementation in Healthcare Personnel

Prospective Evaluation of Breast-Conserving Surgery Alone in Low-Risk Ductal Carcinoma in Situ (DCIS)

Study of OCA in Combination With BZF Evaluating Efficacy, Safety and Tolerability in Participants With PBC

A Study of AZD3427 in Participants With Heart Failure and Pulmonary Hypertension Group 2

HIP Fracture Accelerated Surgical TreaTment And Care tracK 2 Trial

A Registry for Participants With Chronic Hypoparathyroidism

A Study of Ponatinib With Chemotherapy in Children, Teenagers, and Adults With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

A Study to Investigate the Safety and Efficacy of KER-012 in Combination With Background Therapy in Adult Participants With Pulmonary Arterial Hypertension (PAH) (TROPOS Study).