Clinical Trials in Seattle

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Oral Baclofen Pharmacokinetics and Pharmacodynamics in Children With Spasticity

NCT00607542

Oral baclofen is used commonly to treat spasticity in children with cerebral palsy. Although for adults there is dosing,safety and efficacy information in the package insert, this is not the case for children. The purpose of this study is to determine how fast the drug is cleared from the body, the correct dose, and long-term safety and efficacy for children with spasticity.

SpasticityCerebral Palsy

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)61 participantsStarted Nov 2008

Chicago, Illinois, United States • New Orleans, Louisiana, United States • Baltimore, Maryland, United States +8 more locations

COMPLETEDPhase 1/2< 1 mile

Combination Chemotherapy and Total-Body Irradiation Followed by Peripheral Stem Cell or Bone Marrow Transplantation in Treating Patients With Acute Lymphoblastic Leukemia

NCT00027547

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Peripheral stem cell transplantation may be able to replace immune cells that were destroyed by chemotherapy and radiation therapy. Sometimes the transplanted cells are rejected by the body's normal tissues. Mycophenolate mofetil and donor white blood cells may prevent this from happening. PURPOSE: Phase I/II trial to determine the effectiveness of combination chemotherapy and total-body irradiation followed by peripheral stem cell transplantation in treating patients who have acute lymphoblastic leukemia.

Leukemia

Fred Hutchinson Cancer CenterStarted Jul 2001

Portland, Oregon, United States • Seattle, Washington, United States • Leipzig, Germany

Oral Baclofen Pharmacokinetics and Pharmacodynamics in Children With Spasticity

Combination Chemotherapy and Total-Body Irradiation Followed by Peripheral Stem Cell or Bone Marrow Transplantation in Treating Patients With Acute Lymphoblastic Leukemia

Find Trials by Condition in Seattle

Lymphocyte Infusion in Treating Patients With Relapsed Cancer After Bone Marrow or Peripheral Stem Cell Transplantation

Chemotherapy Plus Radiation Therapy and Biological Therapy in Treating Patients With Hematologic Cancer

Gemtuzumab Ozogamicin and Cyclosporine in Treating Older Patients With Relapsed Acute Myeloid Leukemia

SPIRIT III Clinical Trial of the XIENCE V® Everolimus Eluting Coronary Stent System (EECSS)

Fludarabine and Radiation Therapy in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Chronic Phase or Accelerated Phase Chronic Myelogenous Leukemia

Evaluate the Effect of Omalizumab on Markers of Asthma Impairment in Patients With Persistent Allergic Asthma

Magnesium Sulfate For Brain Injury

A Study to Optimize Growth Hormone Dosing in Children With Chronic Kidney Disease by Measuring IGF-1 Levels in Blood

Study Evaluating Desvenlafaxine Succinate Sustained-release (DVS SR) in Adult Outpatients With Pain Associated With Diabetic Peripheral Neuropathy

A Study of Mycophenolate Mofetil (CellCept) in Management of Patients With Lupus Nephritis.

Amevive Wisdom Acquired From Real-Time Evidence (A.W.A.R.E™) Program

Visual Function With Contralateral AcrySof® ReSTOR® Aspheric SN6AD1 and SN6AD3

A Study of Three Doses of TCH346 in Patients With Early Parkinson's Disease to Evaluate Safety and Efficacy

A Study Using Imaging Technology to Measure Changes in Bone Structure After Treatment With Teriparatide

Safety and Effectiveness Study of BCI-540 Versus Placebo in the Treatment of Major Depressive Disorder With Concomitant Anxiety

West Nile Virus Natural History

Evaluation of a Medical Food for Chronic Wounds

Trial of Dacarbazine With or Without Genasense in Advanced Melanoma