Clinical Trials in Seattle

Showing 5801-5820 of 7,135 trials

Sildenafil Trial of Exercise Performance in Idiopathic Pulmonary Fibrosis

NCT00517933

Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease that affects an individual's ability to breathe. This study will evaluate the effectiveness of sildenafil, a medication that increases blood flow to the lungs, at improving breathing function, exercise capacity, and quality of life in people with advanced IPF.

Pulmonary FibrosisHypertension, Pulmonary

Duke University180 participantsStarted Aug 2007

Birmingham, Alabama, United States • Los Angeles, California, United States • San Francisco, California, United States +10 more locations

WITHDRAWNPhase 1< 1 mile

Safety, Pharmacokinetics and Pharmacodynamics of NBI-77860 in Adolescent Females With Congenital Adrenal Hyperplasia

NCT02349503

This is a Phase 1, multicenter, open-label, single-dose study to evaluate the safety and tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of NBI-77860 in subjects with congenital adrenal hyperplasia (CAH). The study will be conducted in approximately 15 adolescent females (12-18 years of age) with a documented medical diagnosis of classic 21-hydroxylase deficiency CAH. The study will include three independent dose cohorts of NBI-77860 (approximately 5 subjects per dose cohort). Ascending doses will be evaluated as part of a sequential-cohort design.

Congenital Adrenal Hyperplasia

Neurocrine BiosciencesStarted Feb 2015

Ann Arbor, Michigan, United States • Seattle, Washington, United States

Sildenafil Trial of Exercise Performance in Idiopathic Pulmonary Fibrosis

Safety, Pharmacokinetics and Pharmacodynamics of NBI-77860 in Adolescent Females With Congenital Adrenal Hyperplasia

Find Trials by Condition in Seattle

Efficacy of a 12-Week Regimen of Telaprevir, Pegylated Interferon, and Ribavirin in Treatment-Naive and Prior Relapser Subjects With Interleukin28B (IL28B) CC Genotype

Red Cell Storage Duration Study

Study of AUY922 and Cetuximab in Patients With KRAS Wild-Type Metastatic Colorectal Cancer

Prevention of Seasonal Affective Disorder

Pomegranate and Hemodialysis Pilot Trial

Shear Wave Ultrasound Elastography in Noninvasive Diagnosis of Thyroid Nodules

Airway Epithelium Gene Expression: AEGIS IDE

A Study of RO4917838 in Patients With Sub-optimally Controlled Symptoms of Schizophrenia (NN25307)

Pelvic Exenteration in Treating Patients With Recurrent Cervical Cancer

Reveal® XT Performance Trial (XPECT)

Study Evaluating the Tolerance and Biologic Activity of Oral Ciclopirox Olamine in Patients With Relapsed or Refractory Hematologic Malignancy

An Open Label Study of the Effect of Telaprevir in Combination With Ribavirin and Peginterferon on HCV Infection in Stable Liver Transplant Patients

A New Prenatal Blood Test for Down Syndrome

Safety and Efficacy of Saxagliptin Plus Insulin With or Without Metformin

Internet-Based Sexual Health Education for Middle School Native American Youth

Study of DTap-IPV Compared to DAPTACEL® and IPOL® as the 5th Dose in Children 4 to 6 Years of Age

Efficacy of Exenatide Once Weekly and Once-Daily Insulin Glargine in Patients With Type 2 Diabetes Treated With Metformin Alone or in Combination With Sulfonylurea (DURATION - 3)

A Randomized Trial of Unruptured Brain AVMs