Clinical Trials in Seattle

Showing 2781-2800 of 9,312 trials

TGRX-678 US Phase I for Subjects with Refractory or Advanced Chronic Myelogenous Leukemia

NCT06088888

The purpose of this single-arm, open-label, dose escalation + cohort expansion study is to evaluate the safety, tolerability, pharmacokinetic and preliminary efficacy of TGRX-678 in Chronic Myelogenous Leukemia patients who had failure with or are intolerant to TKI treatments.

Chronic Myelogenous Leukemia

Shenzhen TargetRx Co., Ltd.90 participantsStarted Jul 2024

Houston, Texas, United States • Seattle, Washington, United States

COMPLETEDPhase 3< 1 mile

Radium-223 Dichloride and Abiraterone Acetate Compared to Placebo and Abiraterone Acetate for Men With Cancer of the Prostate When Medical or Surgical Castration Does Not Work and When the Cancer Has Spread to the Bone, Has Not Been Treated With Chemotherapy and is Causing no or Only Mild Symptoms

NCT02043678

To determine if the addition of radium-223 dichloride to standard treatment is able to prolong life and to delay events specific for prostate cancer which has spread to the bone, such as painful fractures or bone pain which needs to be treated with an X-ray machine.

Prostatic Neoplasms

Bayer806 participantsStarted Mar 2014

Anchorage, Alaska, United States • Tucson, Arizona, United States • Oceanside, California, United States +160 more locations

TGRX-678 US Phase I for Subjects with Refractory or Advanced Chronic Myelogenous Leukemia

Radium-223 Dichloride and Abiraterone Acetate Compared to Placebo and Abiraterone Acetate for Men With Cancer of the Prostate When Medical or Surgical Castration Does Not Work and When the Cancer Has Spread to the Bone, Has Not Been Treated With Chemotherapy and is Causing no or Only Mild Symptoms

Find Trials by Condition in Seattle

A Phase 3 Randomized, Placebo-controlled Trial of Carboplatin and Paclitaxel With or Without Veliparib (ABT-888) in HER2-negative Metastatic or Locally Advanced Unresectable BRCA-associated Breast Cancer

A 3-way Crossover Clinical Investigation to Assess the Performance of Two Different Sized Polyurethane Condoms Versus a Latex Condom in Healthy Monogamous Couples.

Study of Daily Application of Nestorone® (NES) and Testosterone (T) Combination Gel for Male Contraception

Neuroblastoma Precision Trial

Safety and Effectiveness of the MiniMed™ 780G System With DS5 CGM

A Study to Assess the Pharmacodynamics of VK0214 in Male Subjects With AMN

Radiation Therapy With or Without Chemotherapy in Treating Patients With High-Risk Malignant Salivary Gland Tumors That Have Been Removed By Surgery

STOP Persistent AF

Evaluate the Pharmacokinetics and Gonadotropin Suppression of Nestorone®-Testosterone (NES/T) Combination Gel in Men

Pulsed Field Ablation to Irreversibly Electroporate Tissue and Treat AF

Evaluation of the Phased Radio Frequency Ablation System

Evaluation of Lasofoxifene Combined With Abemaciclib in Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

Intracardiac CrYoablation for AtrioVentricular Nodal Reentrant Tachycardia

Study of the Efficacy of Lurasidone in Cognitive Functioning in Bipolar Patients

Trametinib in Treating Patients With Advanced Cancer With or Without Hepatic Dysfunction

A Study to Assess the Safety, Tolerability and Efficacy of IONIS-AGT-LRx in Hypertensive Participants With Uncontrolled Blood Pressure

A Phase 1b Study of Imvotamab in Moderate to Severe Rheumatoid Arthritis

Long-term Follow-up of Participants With Cerebral Adrenoleukodystrophy Who Were Treated With Lenti-D Drug Product