Clinical Trials in San Francisco

Showing 7481-7500 of 9,883 trials

Safety and Pharmacokinetic Study of MM-302 in Patients With Advanced Breast Cancer

NCT01304797

This study is a Phase 1 and pharmacologic open-label dose-escalation trial using a "3+3" design. Successive cohorts of three or more patients will be treated at escalating doses until a maximum tolerated dose is identified. Once the maximum tolerated dose is identified, an Expansion Cohort will be enrolled at that dose to further characterize safety and pharmacologic endpoints. Additional arms will be enrolled to explore the combination of MM-302 with trastuzumab or trastuzumab plus cyclophosphamide in patients with advanced HER2 positive breast cancer.

Breast Cancer

Merrimack Pharmaceuticals75 participantsStarted Mar 2011

San Francisco, California, United States • Indianapolis, Indiana, United States • Boston, Massachusetts, United States +2 more locations

COMPLETEDPhase 3< 1 mile

Radiation Therapy in Treating Patients With Stage II Cancer of the Vocal Cord

NCT00002727

RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known which radiation therapy regimen is more effective in treating patients with stage II cancer of the vocal cord. PURPOSE: Randomized phase III trial to compare two regimens of radiation therapy in treating patients who have stage II cancer of the vocal cord.

Head and Neck Cancer

Radiation Therapy Oncology Group250 participantsStarted Apr 1996

Birmingham, Alabama, United States • Huntsville, Alabama, United States • Huntsville, Alabama, United States +234 more locations

Safety and Pharmacokinetic Study of MM-302 in Patients With Advanced Breast Cancer

Radiation Therapy in Treating Patients With Stage II Cancer of the Vocal Cord

Find Trials by Condition in San Francisco

Efficacy and Safety of Albiglutide in Treatment of Type 2 Diabetes

A Study to Determine the Safety and Efficacy of Albiglutide in Subjects With Type 2 Diabetes

Efficacy and Safety of LAS 34273 in Patients With Moderate to Severe Stable Chronic Obstructive Pulmonary Disease(COPD)

A Randomized Study To Evaluate The Efficacy And Safety Of An Investigational Drug In Adolescent And Adult Subjects With Asthma Uncontrolled on Low-Dose ICS Therapy.

Research Study To Test Carvedilol CR + Lisinopril Versus Lisinopril + Placebo In Patients With High Blood Pressure

An Investigational Drug, PF-02341066 Is Being Studied Versus Standard Of Care In Patients With Advanced Non-Small Cell Lung Cancer With A Specific Gene Profile Involving The Anaplastic Lymphoma Kinase (ALK) Gene

Dual Diagnosis Inpatients: Telephone Monitoring RCT to Improve Outcomes

Effect of Metabolic Control at Onset of Diabetes on Progression of Type 1 Diabetes

A Study of RO6885247 in Adult and Pediatric Patients With Spinal Muscular Atrophy (MOONFISH)

Long-term Extension Study of the Safety, Tolerability, and Efficacy of Aclidinium Bromide in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) (LAS-MD-36)

A Study of Exercise Endurance and Lung Hyperinflation in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

PF-06372865 In Subjects With Chronic Low Back Pain

Glycopyrronium and Formoterol Fumarate (GFF) Metered Dose Inhaler (MDI) Dose Indicator Study in Adults With Moderate to Very Severe COPD

Study To Evaluate Cardiac Assessments Following Different Treatments Of Smoking Cessation Medications In Subjects With And Without Psychiatric Disorders.

Study to Compare U0267 Against Vehicle in Subjects With Plaque-type Psoriasis One of Two Phase 3 Studies

Development of a Blood Test for Marfan Syndrome

A Open Label Phase I/II Clinical Trial to Evaluate CPI-613 in Patients With Advanced Malignancies

Continuous Chest Compressions vs AHA Standard CPR of 30:2