Clinical Trials in San Francisco

Showing 5781-5800 of 9,883 trials

Safety Study of a Dual Anti-HIV Gene Transfer Construct to Treat HIV-1 Infection

NCT01734850

This is an early phase research study looking at whether an experimental gene transfer, LVsh5/C46 (also known as Cal-1), is safe and if it can protect the immune system from the effects of HIV without the use of antiretroviral drugs. Cal-1 is an experimental gene transfer agent designed to inhibit HIV infection through 2 active parts: 1. Removing a protein named CCR5 from bone marrow and white blood cells 2. Producing a protein named C46 on bone marrow and white blood cells

Human Immunodeficiency Virus

Calimmune, Inc.13 participantsStarted Apr 2013

Los Angeles, California, United States • San Francisco, California, United States

COMPLETEDPhase 1< 1 mile

Ipilimumab and Sargramostim in Treating Patients With Metastatic Prostate Cancer

NCT00064129

This phase I trial is studying the side effects and best dose of ipilimumab when given with sargramostim in treating patients with metastatic prostate cancer. Monoclonal antibodies can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. Colony-stimulating factors, such as sargramostim, may increase the number of immune cells found in bone marrow or peripheral blood and may help a person's immune system kill more tumor cells.

Recurrent Prostate CarcinomaStage IV Prostate Cancer AJCC v7

National Cancer Institute (NCI)42 participantsStarted May 2003

San Francisco, California, United States

COMPLETEDPhase 38.4 miles

Study of the Efficacy and Safety of Intravitreal (IVT) Aflibercept for the Improvement of Moderately Severe to Severe Nonproliferative Diabetic Retinopathy (NPDR)

NCT02718326

The primary objective of the study is to assess the efficacy of intravitreal (IVT) aflibercept compared to sham treatment in the improvement of moderately severe to severe nonproliferative diabetic retinopathy (NPDR). The secondary objectives of the study are: * To characterize the safety of IVT aflibercept in patients with moderately severe to severe NPDR * To determine if IVT aflibercept will prevent the worsening of diabetic retinopathy and reduce the incidence of DME * To determine the anatomic effects of IVT aflibercept in patients with moderately severe to severe NPDR

Nonproliferative Diabetic Retinopathy

Regeneron Pharmaceuticals402 participantsStarted Mar 2016

Phoenix, Arizona, United States • Tucson, Arizona, United States • Arcadia, California, United States +86 more locations

Safety Study of a Dual Anti-HIV Gene Transfer Construct to Treat HIV-1 Infection

Ipilimumab and Sargramostim in Treating Patients With Metastatic Prostate Cancer

Study of the Efficacy and Safety of Intravitreal (IVT) Aflibercept for the Improvement of Moderately Severe to Severe Nonproliferative Diabetic Retinopathy (NPDR)

Find Trials by Condition in San Francisco

Clinical Evaluation of Daily Disposable Contact Lenses

A Dispensing Clinical Trial of Comfilcon A Extended Range Multifocal Lenses

Safety and Efficacy of Saracatinib In Subjects With Lymphangioleiomyomatosis

Genomic Analysis of Pediatric Bone Tumors

A Study to Evaluate Abicipar Pegol for Safety and Treatment Effect in Participants With Neovascular Age-related Macular Degeneration (AMD)

A Safety and Efficacy Study of Abicipar Pegol in Participants With Neovascular Age-related Macular Degeneration

Efficacy and Safety of Intravenous Neridronic Acid in Complex Regional Pain Syndrome (CRPS)

Long-term Observational Study of Subjects From Tanezumab Studies Who Undergo a Total Knee, Hip or Shoulder Replacement

Early Feasibility Study of the Percutaneous 4Tech TriCinch Coil Tricuspid Valve Repair System

Irinotecan and Paclitaxel in Treating Patients With Metastatic or Recurrent Cancer of the Esophagus or Stomach

PREMIUM Migraine Trial

A Study to Evaluate the Long-Term Safety and Efficacy of GDC-0853 in Participants With Moderate to Severe Rheumatoid Arthritis Enrolled in Study GA29350

A Phase III Efficacy and Safety Study of Intravenous Retosiban Versus Placebo for Women in Spontaneous Preterm Labor

Multi-Center Study of New Medications to Treat Vaginal Infections

Self-management to Improve Function Following Amputation

INSPIRE: Internet and Social-media Program With Information and Resources for Long-Term Cancer Survivors Who Underwent Stem Cell Transplant

Effectiveness and Safety of CELSTAT for Hemostasis in Intraoperative Tissue Bleeding