Clinical Trials in San Diego

Showing 10521-10540 of 12,589 trials

California Transport Cooling Trial

NCT01683383

Hypoxic ischemic encephalopathy (HIE) remains a major cause of death and severe disability despite advances in neonatal and perinatal medicine. Therapeutic hypothermia is the single most promising intervention for HIE. Reduction of brain temperature by 2° to 5°C has shown to be neuroprotective in newborn and adult animal models of brain ischemia. Therapeutic hypothermia instituted within 6 hours of birth has been shown to significantly improve survival and neurodevelopmental outcome in term newborns with HIE. Hypothermia is most effective if begun during the latent period, before the secondary energy failure. It is not known whether cooling initiated after 6 hours of age is effective. The goal of this proposal is to test the efficacy of the cooling device in achieving the target temperatures in patients with moderate to severe HIE during transport when compared with current practices.

Hypoxic Ischemic Encephalopathy

Stanford University101 participantsStarted Sep 2012

Loma Linda, California, United States • Madera, California, United States • Oakland, California, United States +6 more locations

COMPLETEDPhase 2/3< 1 mile

In-vivo Analysis and Clinical Evaluation of the Performance of a Fractional CO2 Laser System (eMatrixCO2)

NCT00992277

This study will: Evaluate the in vivo histological and molecular effects of treatment with eMatrixCO2 and to determine the dynamics of their development over time following treatment. Determine the safety and efficacy of treatment with eMatrixCO2 for use in Aesthetic dermatological procedures requiring the ablation, vaporization, excision, incision, or coagulation of soft tissue.

Aesthetic Dermatology

Syneron Medical25 participantsStarted Oct 2009

San Diego, California, United States • Tustin, California, United States • Saint Edina, Minnesota, United States

California Transport Cooling Trial

In-vivo Analysis and Clinical Evaluation of the Performance of a Fractional CO2 Laser System (eMatrixCO2)

Find Trials by Condition in San Diego

A Study of the Safety and Efficacy of Two Doses of Naltrexone SR/Bupropion SR and Placebo in Overweight and Obese Subjects

Study of a Single Dose of Menactra® Vaccine 4-6 Years After Prior Menactra Vaccine

Study to Determine the Safety, Tolerability, Pharmacokinetics, Food Effect and Pharmacodynamics of Single and Multiple Ascending Doses of P7435 in Healthy, Overweight or Obese Subjects

Open-label Extension Evaluating Methylphenidate Hydrochloride Extended Release in Adults With Attention Deficit/Hyperactivity Disorder

SMART: A Social and Mobile Weight Control Program for Young Adults

Planned CORR: Planned Care for Obesity and Risk Reduction

Validation of Objective Measures of Place-Based Physical Activity

Lung Protective Ventilation in Pulmonary Thromboendarterectomy (PTE) Patients

Lifestyle Change Program in Elderly Patients With Heart Failure

Comparison of LDL Particle Count With Other Available Lipid Tests

Co-administration of Olodaterol Respimat® and Tiotropium Handihaler®

Comparison of Delivery Routes of Flu Vaccine in Adults

Naturlose (D-Tagatose) Efficacy Evaluation Trial

CARTO® 3 System and Real Time Intracardiac Ultrasound

Monotherapy Pazopanib in Subjects With Advanced Non-Small Cell Lung Cancer

A Clinical Assessment Study of Subjects With Mucopolysaccharidosis IVA (Morquio Syndrome)

DPBRN Reasons for Placing the First Restoration on Permanent Tooth Surfaces

Linagliptin in Combination With Metformin in Treatment Naive Patients With Type 2 Diabetes Mellitus and Insufficient Glycaemic Control