Clinical Trials in San Diego

Showing 6761-6780 of 14,679 trials

Ibrutinib and Azacitidine for Treatment of Higher Risk Myelodysplastic Syndrome

NCT02553941

This phase Ib trial studies the side effects and best dose of ibrutinib when given together with azacitidine in treating patients with myelodysplastic syndrome that is likely to occur or spread (higher risk) and who were previously treated or untreated and unfit for or refused intense therapy. Ibrutinib and azacitidine may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.

Chronic Myelomonocytic Leukemiade Novo Myelodysplastic SyndromePreviously Treated Myelodysplastic Syndrome+2 more

Brian Jonas21 participantsStarted May 2016

Los Angeles, California, United States • Orange, California, United States • Sacramento, California, United States +2 more locations

COMPLETEDPhase 1/2< 1 mile

Biomarker Strategies for Medication-Enhanced Cognitive Training in Schizophrenia

NCT01555697

Cognitive training is moderately effective at reducing symptoms and improving life function in schizophrenia patients. The present application develops a strategy for increasing the effectiveness of cognitive training through the use of pro-cognitive medications. Specific biomarkers will be studied that identify patients most sensitive to these pro-cognitive medications, to test the feasibility of using these biomarkers in a large clinical trial of medication-enhanced cognitive training in schizophrenia.

Schizophrenia

University of California, San Diego80 participantsStarted Jul 2014

San Diego, California, United States

Ibrutinib and Azacitidine for Treatment of Higher Risk Myelodysplastic Syndrome

Biomarker Strategies for Medication-Enhanced Cognitive Training in Schizophrenia

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Trial to Reduce Sitting Time in Postmenopausal Latina Women at Increased Risk for Heart Disease

Phase III Study of Lenalidomide and Dexamethasone With or Without Elotuzumab to Treat Newly Diagnosed, Previously Untreated Multiple Myeloma

Study to Evaluate the Safety and Efficacy of High Dose Intravenous Immune Globulin (IVIG) Plus Standard Medical Treatment (SMT) Versus SMT Alone in Participants in Intensive Care Unit (ICU) With Coronavirus Disease (COVID-19)

Mifepristone Treatment of Alcohol Use Disorder

A Study of the Safety and Pharmacokinetics of Apixaban Versus Vitamin K Antagonist (VKA) or Low Molecular Weight Heparin (LMWH) in Pediatric Subjects With Congenital or Acquired Heart Disease Requiring Anticoagulation

A Phase III Study to Evaluate the Port Delivery System With Ranibizumab Compared With Monthly Ranibizumab Injections in Participants With Wet Age-Related Macular Degeneration

Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Efficacy of Evixapodlin (Formerly GS-4224) in Participants With Advanced Solid Tumors

Open Label Extension to Assess the Safety of Long-Term Treatment With Ampion for Severe Osteoarthritis (OA) of the Knee

TH9507 Extension Study in Patients With HIV-Associated Lipodystrophy

Study of Vadadustat in Hemodialysis Participants With Anemia Switching From Epoetin Alfa

P1 Single and Multiple Ascending Dose (SAD/MAD) Study of IV QPX7728 Alone and Combined With QPX2014 in NHV

Effects of Therapy With Sulfamylon® 5% Topical Solution Compared to a Historical Control Group

Dysport® Adult Upper Limb Spasticity Extension Study

Safety and Efficacy of Nerinetide (NA-1) in Subjects Undergoing Endovascular Thrombectomy for Stroke

Physiologic Signals and Signatures With the Accuryn Monitoring System - The Accuryn Registry

(VOYAGER) Study of Avapritinib vs Regorafenib in Patients With Locally Advanced Unresectable or Metastatic GIST

A Study of ALRN-6924 for the Prevention of Chemotherapy-induced Side Effects (Chemoprotection)

Does the Cap Increase the Finding of Polyps When Water Exchange Colonoscopy is Used