Clinical Trials in San Diego

Showing 4941-4960 of 11,146 trials

Thoracolumbar Burst Fractures Study Comparing Surgical Versus Non-surgical Treatment

NCT02827214

Thoracolumbar (TL) burst fractures in neurologically intact patients account for approximately 45% of all TL spine injuries. Despite being common fractures, there is significant variability in treatment recommendations encompassing surgery and non-surgical treatment options. The controversy regarding optimal treatment for these injuries is fueled by several studies which suggest a potential benefit to surgical treatment in the realm of patient satisfaction, and the overall socio-economic burden of treatment while other studies demonstrate improved outcomes and lower morbidity with non-surgical treatment. This study aims to perform a prospective cohort analysis investigating the clinical outcome of various treatment alternatives for patients with A3/A4 fractures in the thoracolumbar region. A cost-effectiveness analysis will also be performed to identify costs and benefits of each treatment option. More specifically a sub-group analysis will be performed for this group of patients, which have equipoise in regards to patients treatment, as decided by a blinded review panel.

Thoracolumbar Burst Fracture

AO Innovation Translation Center213 participantsStarted Oct 2016

San Diego, California, United States • East Syracuse, New York, United States • Philadelphia, Pennsylvania, United States +11 more locations

COMPLETEDPhase 3< 1 mile

Effectiveness and Safety of BMS-986165 Compared to Placebo and Active Comparator in Participants With Psoriasis

NCT03624127

The purpose of this study is to investigate the experimental medication BMS-986165 compared to placebo and a currently available treatment in participants with moderate to severe plaque psoriasis.

Psoriasis

Bristol-Myers Squibb666 participantsStarted Aug 2018

Birmingham, Alabama, United States • Mobile, Alabama, United States • Phoenix, Arizona, United States +162 more locations

Thoracolumbar Burst Fractures Study Comparing Surgical Versus Non-surgical Treatment

Effectiveness and Safety of BMS-986165 Compared to Placebo and Active Comparator in Participants With Psoriasis

Find Trials by Condition in San Diego

Study to Evaluate the Safety and Preliminary Efficacy of IDCT, a Treatment for Symptomatic Lumbar Intervertebral Disc Degeneration

Observational Study of Long Acting Injectable Medications (LAIs) in Schizophrenia (OASIS)

A Study of Baricitinib (LY3009104) in Participants With Systemic Lupus Erythematosus

Inhaled ZYESAMI™ (Aviptadil Acetate) for the Treatment of Severe COVID-19

Study of the Safety and Efficacy of OPC-34712 as a Complementary Therapy in the Treatment of Adult Attention Deficit/Hyperactivity Disorder

A Study of Atezolizumab in Combination With Bevacizumab Versus Sunitinib in Participants With Untreated Advanced Renal Cell Carcinoma (RCC)

A Phase 3 Study of NI-071 in Participants With Rheumatoid Arthritis (RADIANCE)

PROTECTED TAVR: Stroke PROTECTion With SEntinel During Transcatheter Aortic Valve Replacement

Androgen Reduction in Congenital Adrenal Hyperplasia

Study of Efficacy and Safety of Reinfusion of Tisagenlecleucel in Pediatric and Young Adult Patients With Acute Lymphoblastic Leukemia (ALL)

Efficacy and Safety of Norketotifen in Uncomplicated Influenza-like Illness

Study Tests Whether a Standardized LVR Performed With the Blue Egg Device Improves Cardiopulmonary Exercise Capacity

A Study to Assess the Safety and Tolerability of Different Doses of AG019 Administered Alone or in Combination With Teplizumab in Participants With Recent-onset Diagnosed Type 1 Diabetes (T1D)

Assessing the Efficacy and Safety of Brolucizumab Versus Aflibercept in Patients With Visual Impairment Due to Macular Edema Secondary to Branch Retinal Vein Occlusion

Shape Up! Kids Study

Rectal Microbicide Acceptability, Tolerability and Adherence

A Performance Evaluation Study of Arquer's MCM5 Elisa Test (ADXBLADDER) to Aid in the Monitoring of Recurrence in Non-Muscle Invasive Bladder Cancer

Neuro RX Gamma - Pivotal Phase