Clinical Trials in San Diego

Showing 4521-4540 of 11,146 trials

Effects of Emicizumab vs. Factor VIII Prophylaxis on Joint and Bone Health in Severe Hemophilia A

NCT04131036

The investigators propose to study longitudinal joint and bone density changes in patients with severe Hemophilia A. Per current standard of care, most patients are on prophylactic FVIII replacement therapy intravenously several times weekly with a goal of keeping the trough \>1% FVIII. Recent phase 3 data suggest superior bleed protection with emicizumab prophylaxis every 1-2 weeks. It is the purpose of this study to longitudinally assess joint health and bone density over 3 years and to compare the effect of routine factor VIII prophylaxis with emicizumab prophylaxis.

Hemophilia A

Washington Institute for Coagulation40 participantsStarted Apr 2019

Los Angeles, California, United States • San Diego, California, United States • San Antonio, Texas, United States +1 more locations

COMPLETED< 1 mile

Clinical Validation of An Optimized Multi-Target Stool DNA (Mt-sDNA 2.0) Test, for Colorectal Cancer Screening "BLUE-C"

NCT04144738

The primary objective of this study is to assess the sensitivity for colorectal cancer (CRC) and specificity of the mt-sDNA 2.0 test.

Colorectal Cancer

Exact Sciences Corporation26,758 participantsStarted Nov 2019

Birmingham, Alabama, United States • Birmingham, Alabama, United States • Birmingham, Alabama, United States +192 more locations

Effects of Emicizumab vs. Factor VIII Prophylaxis on Joint and Bone Health in Severe Hemophilia A

Clinical Validation of An Optimized Multi-Target Stool DNA (Mt-sDNA 2.0) Test, for Colorectal Cancer Screening "BLUE-C"

Find Trials by Condition in San Diego

Dose-Ranging Efficacy and Safety Study of Topical Rapamycin Cream for Facial Angiofibroma Associated With Tuberous Sclerosis Complex

Dociparstat Sodium (CX-01) Combined With Standard Induction Therapy for Newly Diagnosed Acute Myeloid Leukemia

Impact of Acetaminophen on Performance of Guardian™ Sensor (3) in Adults

Safety and Efficacy of Pilocarpine Ophthalmic Topical Cream for the Treatment of Presbyopia

Real World Evaluation of the Effectiveness of AZD7442 for Prevention of SARS-CoV-2

A Long-Term Extension Trial in Participants With Atopic Dermatitis Who Participated in Previous EDP1815 Trials

Efficacy and Safety of Orally Administered BBT-401-1S in Subjects With Ulcerative Colitis

A Phase 1b Study to Evaluate APL-1401 in Patients With Moderately to Severely Active Ulcerative Colitis

Intermittent Hypoxia and Caffeine in Infants Born Preterm

A Study of Duvelisib in Participants With Refractory Indolent Non-Hodgkin Lymphoma

Observation or Radiation Therapy in Treating Patients With Grade I, Grade II, or Grade III Meningioma

Study of Emerfetamab (AMG 673) in Adults With Relapsed/Refractory Acute Myeloid Leukemia (AML)

Study to Assess the Efficacy and Safety of Rilonacept Treatment in Participants With Recurrent Pericarditis

High Dose IL 2 and Entinostat in RCC

Studying Tissue and Blood Samples From Patients With Acute Myeloid Leukemia

Safety and Immunotherapeutic Activity of Cemiplimab in Participants With HBV on Suppressive Antiviral Therapy

Low-Dose Atropine for Treatment of Myopia

Evidence-based Stimulation Trial With Human rFSH in Europe and Rest of World 2