Clinical Trials in San Diego

Showing 4041-4060 of 13,391 trials

Real-Time Levodopa Level Monitoring in Parkinson Disease

NCT04735627

This project aims to develop a minimally invasive sensor device to monitor levodopa levels in real time. We will test the accuracy, tolerability, and safety of this device in people with Parkinson disease.

Parkinson Disease

University of California, San Diego20 participantsStarted Dec 2021

San Diego, California, United States

COMPLETEDPhase 2< 1 mile

Open-Label Study of Setmelanotide in Hypothalamic Obesity

NCT04725240

Open-label, single-arm study designed to evaluate the body weight response to setmelanotide administered subcutaneously (SC) daily in participants with hypothalamic obesity (HO).

Hypothalamic Obesity

Rhythm Pharmaceuticals, Inc.18 participantsStarted Jun 2021

San Diego, California, United States • Gainesville, Florida, United States • Saint Paul, Minnesota, United States +2 more locations

COMPLETEDPhase 26.9 miles

A Study Evaluating the Safety, Tolerability, and Pharmacodynamic Effects of GLY-200 in Type 2 Diabetic Patients

NCT05478525

This study is a Phase 2, randomized, double-blind, placebo-controlled, single-center study in adult patients with type 2 diabetes. It will evaluate the safety and tolerability of oral GLY-200. Subjects will participate in a ≤ 18-day screening period followed by a metformin washout period of approximately 14 days, and an inpatient period of 16 days. Approximately 48 subjects will be randomized to 1 of 3 active treatment groups or 1 of 3 placebo groups. Dosing will occur for 14 days. A follow-up clinic visit will occur on Day 21 \[End of Study (EOS)\] or Early Termination (ET).

Type 2 Diabetes

Glyscend, Inc.51 participantsStarted Aug 2022

Chula Vista, California, United States

Real-Time Levodopa Level Monitoring in Parkinson Disease

Open-Label Study of Setmelanotide in Hypothalamic Obesity

A Study Evaluating the Safety, Tolerability, and Pharmacodynamic Effects of GLY-200 in Type 2 Diabetic Patients

Find Trials by Condition in San Diego

Different Doses of Naronapride Vs. Placebo in Gastroparesis

A Study of XmAb20717 (Vudalimab)in Patients With Selected Advanced Gynecologic and Genitourinary Malignancies

Single Center Exploratory Study To Evaluate The Use Of The RxSight Light Adjustable Lens (LAL) And The Light Delivery Device (LDD) To Improve Visual Outcomes

Rising Tide - Amniotic Tissue(s) Treatments for Chronic Diabetic Foot Ulcers

Study on BI 54903 (Inhaled Corticosteroid) Administered Twice Daily Via Respimat Inhaler in Patients With Asthma Inadequately Controlled on Medium Dose Inhaled Corticosteroid (ICS).

A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Upadacitinib in Pediatric Participants With Severe Atopic Dermatitis

(Concerto) Study of BLU-451 in Advanced Cancers With EGFR Exon 20 Insertion Mutations

Futibatinib Versus Gemcitabine-Cisplatin Chemotherapy as First-Line Treatment of Patients With Advanced Cholangiocarcinoma Harboring FGFR2 Gene Rearrangements

DS-3201b in Participants With Lymphomas

A Study of AK117 in Combination With Azacitidine in Patients With Myelodysplastic Syndromes

Clinical Trial to Assess Efficacy and Safety of the Human Anti-CD38 Antibody Felzartamab (MOR202) in IgA Nephropathy

A Study of SGN-ALPV in Advanced Solid Tumors

A Study of Participants with Β-Thalassemia Treated with Betibeglogene Autotemcel

A Clinical Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of PGDM1400LS Alone and in Combination With VRC07-523LS and PGT121.414.LS in Healthy, HIV-uninfected Adult Participants

A Trial of a Novel XPO1 Inhibitor in Participants With Advanced Solid Tumors

LDK378 Versus Chemotherapy in ALK Rearranged (ALK Positive) Patients Previously Treated With Chemotherapy (Platinum Doublet) and Crizotinib

A Study of the Safety and Tolerability in Participants With PIK3CA-related Overgrowth Spectrum or Proteus Syndrome Who Are Being Treated With Miransertib (MK-7075) in Other Studies (MK-7075-006)