Clinical Trials in San Diego

Showing 3181-3200 of 7,028 trials

CERE-110 in Subjects With Mild to Moderate Alzheimer's Disease

NCT00087789

This is a Phase I clinical study to assess the safety, tolerability and biologic activity of in vivo AAV-mediated delivery of CERE-110. Up to 12 subjects will receive open label CERE-110 in dose-escalating fashion. All subjects will receive bilateral, stereotactic injections of CERE-110 for a total of four (Dose A and B) and six (Dose C) injections to target the basal forebrain region of the brain containing the nucleus basalis of Meynert (NBM). All study participants will be observed for a 24-month period and then followed annually.

Alzheimer's Disease

Sangamo Therapeutics10 participantsStarted Jun 2004

San Diego, California, United States • Chicago, Illinois, United States

COMPLETEDPhase 3< 1 mile

RED-HF™ Trial - Reduction of Events With Darbepoetin Alfa in Heart Failure Trial

NCT00358215

The purpose of the study is to determine the efficacy of treatment of anemia with darbepoetin alfa compared to placebo on the composite of time to death from any cause or first hospital admission for worsening heart failure in patients with symptomatic left ventricular systolic dysfunction and anemia.

Heart FailureAnemiaCardiovascular Disease+2 more

Amgen2,278 participantsStarted Jun 2006

Birmingham, Alabama, United States • Birmingham, Alabama, United States • Huntsville, Alabama, United States +751 more locations

CERE-110 in Subjects With Mild to Moderate Alzheimer's Disease

RED-HF™ Trial - Reduction of Events With Darbepoetin Alfa in Heart Failure Trial

Find Trials by Condition in San Diego

Phase 2 Study of BIIB092 in Participants With Early Alzheimer's Disease

LDL-C Assessment With PCSK9 Monoclonal Antibody Inhibition Combined With Statin Therapy-2

Effect of Sotagliflozin on Cardiovascular Events in Participants With Type 2 Diabetes Post Worsening Heart Failure (SOLOIST-WHF Trial)

Phase 3 Study With Carfilzomib and Dexamethasone Versus Bortezomib and Dexamethasone for Relapsed Multiple Myeloma Patients

A Study of INCB018424 Phosphate Cream in Subjects With Vitiligo

A Study of Recombinant Vaccinia Virus in Combination With Cemiplimab for Renal Cell Carcinoma

A Study of Escitalopram in the Treatment of Children and Adolescents With Generalized Anxiety Disorder

A Study to Investigate CSL312 in Subjects With Hereditary Angioedema (HAE)

Rofecoxib Efficacy and Safety Evaluation Trial in Hemophilic Arthropathy

A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma

Predictive Assay for Decision Making in Adjuvant Therapy

THE ALIGN-AR EFS TRIAL: JenaValve Pericardial TAVR Aortic Regurgitation Study

A Phase III Trial of Niraparib Versus Physician's Choice in HER2 Negative, Germline BRCA Mutation-positive Breast Cancer Patients

Vascular Inflammation in Psoriasis - Apremilast

A Safety, Pharmacokinetic & Dose-Escalation Study of KD019 in Subjects With Autosomal Dominant Polycystic Kidney Disease

Efficacy and Safety Study of Postsurgical Analgesia With INL-001 in Abdominoplasty

Implementing an Individualized Pain Plan (IPP) for ED Treatment of VOE's in Sickle Cell Disease

An Investigational Immuno-therapy Trial of Pomalidomide and Low-dose Dexamethasone With or Without Elotuzumab to Treat Refractory and Relapsed and Refractory Multiple Myeloma (ELOQUENT-3)