Clinical Trials in San Antonio

Showing 4541-4560 of 14,633 trials

Study of Selinexor Plus DRd for Newly Diagnosed Multiple Myeloma

NCT04782687

This is a single-arm, phase II, open-label trial to investigate the effects of selinexor (S) in combination with daratumumab, lenalidomide, and dexamethasone (DRd) for first-line treatment of multiple myeloma (MM). FDA has approved selinexor plus dexamethasone in multiple myeloma after four prior therapies, and DRd is also already approved by the FDA for multiple myeloma. This study will use all four (S-DRd) together to treat MM as an initial treatment.

Multiple MyelomaMyeloma MultipleKahler Disease+4 more

US Oncology Research73 participantsStarted Sep 2021

Tucson, Arizona, United States • Denver, Colorado, United States • Columbia, Maryland, United States +7 more locations

COMPLETEDNA< 1 mile

CLUSTER Trial for Outbreak Detection and Response

NCT04053075

Despite the critical importance of identifying hospital-associated outbreaks as early as possible in order to limit their spread, there are currently no standardized methods for cluster detection. The CLUSTER Trial (Cluster Linkage Using Statistics to Trigger and Evaluate Response) will assess whether a statistically-based automated cluster detection method coupled with a robust response protocol will enable rapid containment of hospital clusters as measured by a reduction in cluster size and duration as compared to routine hospital cluster detection methods coupled with the same response protocol. Note: that enrolled "subjects" represents 82 individual HCA Healthcare hospitals that have been randomized

Cluster Detection

Harvard Pilgrim Health Care2,905,455 participantsStarted Jul 2019

Riverside, California, United States • San Jose, California, United States • Thousand Oaks, California, United States +79 more locations

Study of Selinexor Plus DRd for Newly Diagnosed Multiple Myeloma

CLUSTER Trial for Outbreak Detection and Response

Find Trials by Condition in San Antonio

A First in Human Study of ORT247 in Healthy Volunteers

Safety, Tolerability, and Pharmacokinetics of Clesrovimab (MK-1654) in Infants (MK-1654-002)

ACP-104 in Acutely Psychotic Subjects With Schizophrenia

Saypha® VOLUME Lidocaine for Midface Augmentation

PERSEVERE- A Trial to Evaluate AMDS in Acute DeBakey Type I Dissection

ACX-362E [Ibezapolstat] for Oral Treatment of Clostridioides Difficile Infection

Azacitidine With or Without Nivolumab or Midostaurin, or Decitabine and Cytarabine Alone in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Stereotactic Laser Ablation for Temporal Lobe Epilepsy (Slate)

Expanded Access for the Treatment of Cancers With Rearranged During Transfection (RET) Activation

Non-Complex Biliary Stones DSC vs ERC

Clinical Evaluation of the StablePoint Catheter and Force Sensing System for Paroxysmal Atrial Fibrillation

Feasibility Study of Intraoperative Detection of Residual Cancer in Breast Cancer Patients

Study to Assess the Efficacy and Safety of NBI-1065845 in Adults With Major Depressive Disorder (MDD)

Safety and Treatment Satisfaction in Adults With Chronic ITP After Switching to Avatrombopag From Eltrombopag or Romiplostim

Assessment of Financial Difficulty in Participants with Chronic Lymphocytic Leukemia and Multiple Myeloma

Safety of a Three-Day Fosaprepitant Regimen for the Prevention of Chemotherapy-Induced Nausea and Vomiting in Pediatric Participants (MK-0517-045)

A Study to Evaluate the Safety, and Tolerability, and Efficacy of Seladelpar in Patients With PSC

Heart EXPAND Continued Access Protocol