Clinical Trials in Salt Lake City

Showing 5921-5940 of 12,670 trials

Lovastatin for the Treatment of Mildly Active Rheumatoid Arthritis

NCT00302952

Rheumatoid arthritis (RA) is the most common inflammatory arthritis and a major health problem. The purpose of this study is to determine the safety and effectiveness of lovastatin for controlling inflammation in mildly active RA.

Rheumatoid Arthritis

National Institute of Allergy and Infectious Diseases (NIAID)64 participantsStarted Nov 2007

Birmingham, Alabama, United States • San Francisco, California, United States • Aurora, Colorado, United States +12 more locations

UNKNOWNPhase 2< 1 mile

An Exploratory, Open-Label, Oligo-Center Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Intravenous DNV3837 in Subjects With Clostridium Difficile Infection

NCT03988855

This is an open-label study to evaluate the safety, efficacy, and PK of DNV3837 at a dose of 1.5 mg/kg actual body weight(BW)/day administered via IV infusion in subjects with CDI. The study will be conducted in 2 subsequent parts. In Part 1 of the study, 10 subjects of either sex with severe or non-severe CDI will be enrolled to receive DNV3837. In Part 2 of the study, up to 30 subjects with severe or non-severe CDI will be enrolled to receive DNV3837. In both parts of the study, treatment infusions will be administered at a constant rate resulting in a total IV infusion duration of 6 hours per day, for a total maximum daily dose of 120 mg DNV3837. Infusions will be administered once daily for 10 consecutive days. The objectives of the study are: * To evaluate the safety of intravenous (IV) DNV3837; * To evaluate the efficacy of IV DNV3837; * To assess the pharmacokinetics (PK) of DNV3837 and DNV3681 in plasma and of DNV3681 in urine and feces; * To assess C. difficile using microbiological assessments; * To assess the proportion of subjects colonized with vancomycin-resistant enterococci (VRE), extended-spectrum beta-lactamase (ESBL) organisms, or carbapenem-resistant Enterobacteriaceae (CRE) in feces; and * To assess changes in the fecal microbiome using 16S ribosomal ribonucleic acid (RNA) analysis

Clostridium Difficile (C. Difficile)

Deinove40 participantsStarted Aug 2019

Anniston, Alabama, United States • Sacramento, California, United States • Idaho Falls, Idaho, United States +10 more locations

Lovastatin for the Treatment of Mildly Active Rheumatoid Arthritis

An Exploratory, Open-Label, Oligo-Center Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Intravenous DNV3837 in Subjects With Clostridium Difficile Infection

Find Trials by Condition in Salt Lake City

Safety, Tolerability, and Efficacy of AXA1125 in NASH With Fibrosis

Subject Satisfaction With AbobutulinumtoxinA Treatment

Dose Escalation of RMC-4630 Monotherapy in Relapsed/Refractory Solid Tumors

Study to Assess if ABP798 is Safe & Effective in Treating Non Hodgkin Lymphoma Compared to Rituximab

Evaluation of the Use of Medical Scribes in VAMC Emergency Departments and Specialty Care Clinics

A Study to Investigate Intravenous Tocilizumab in Participants With Moderate to Severe COVID-19 Pneumonia

A Study of Experimental Medication BMS-986036 in Adults With Nonalcoholic Steatohepatitis (NASH) and Stage 3 Liver Fibrosis

Phase 3 Study of OTX-101 in the Treatment of Keratoconjunctivitis Sicca

Study to Evaluate the Safety and Efficacy of SDP-4 in Subjects With Dry Eye Disease (DED)

Safety and Efficacy Study of DUR-928 Topical Solution in Subjects With Plaque Psoriasis

A Treatment Use Protocol for Subjects Continuing on From the Open-label Extension 0601

The Safety, Efficacy and Pharmacokinetics of ARQ-151 Cream in Subjects With Chronic Plaque Psoriasis

A Comparison Study of LY2140023 and Aripiprazole in Schizophrenia Patients

A Study of LY2140023 in Schizophrenia Patients With Prominent Negative Symptoms

Long-term Neurocognitive Sequelae of Subclinical Microembolization During Carotid Interventions

Feasibility Study for GORE® TAG® Thoracic Branch Endoprosthesis to Treat Proximal Descending Thoracic Aortic Aneurysms

Cinrebafusp Alfa in Combination With Ramucirumab and Paclitaxel in HER2-High Gastric or GEJ Adenocarcinoma and in Combination With Tucatinib in HER2-Low Gastric or GEJ Andenocarinoma

A Prospective Study of Early Mechanical Stabilization and Bleeding in Disruption of the Pelvic Ring