Clinical Trials in Salt Lake City

Showing 4781-4800 of 16,694 trials

Etonogestrel (ENG) Implant Insertion for Emergency Contraception With Oral Levonorgestrel (LNG) vs Placebo

NCT06162611

Intrauterine devices (IUDs) are highly effective to prevent pregnancy when used for emergency contraception (following unprotected intercourse in the last 3 days), but data are lacking for people who desire an etonogestrel (ENG) contraceptive implant in this situation. This proposal will identify the most effective way to start an implant for emergency contraception using a randomized controlled trial comparing pregnancy risk between those receiving the implant vs. the implant plus oral emergency contraception (EC). Data from this project will inform clinical practice and add another option, the implant, for those desiring a long acting, highly effective contraceptive method when they present for emergency contraception.

Emergency Contraception

Lori Gawron790 participantsStarted Nov 2023

Salt Lake City, Utah, United States

COMPLETEDPhase 1< 1 mile

A Multiple-dose Study of ASP8374, an Immune Checkpoint Inhibitor, as a Single Agent and in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors

NCT03260322

The primary purpose of this study is to evaluate the tolerability and safety profile of ASP8374 when administered as a single agent and in combination with pembrolizumab in participants with locally advanced (unresectable) or metastatic solid tumor malignancies. Also primary purpose is to characterize the pharmacokinetic profile of ASP8374 when administered as a single agent and in combination with pembrolizumab. Last primary purpose of this study is to determine the recommended Phase 2 dose (RP2D) of ASP8374 when administered as a single agent and in combination with pembrolizumab. The secondary purpose of this study is to evaluate the anti-tumor effect (objective response rate \[ORR\], duration of response \[DOR\], persistence of response after discontinuation, and disease control rate \[DCR\]) of ASP8374 when administered as a single agent and in combination with pembrolizumab. NTP: Neutropenia NHAE:Non-haematological AE GBS: Guillain-Barré syndrome"" IRR: Infusion-related reaction AST: Aspartate aminotransferase ALT: Alanine aminotransferase MS/MG: Myasthenia Syndrome/Myasthenia Gravis TRT: Treatment-related Toxicity TCP: Thrombocytopenia

Advanced Solid Tumors

Astellas Pharma Global Development, Inc.169 participantsStarted Sep 2017

Scottsdale, Arizona, United States • Los Angeles, California, United States • Los Angeles, California, United States +51 more locations

Etonogestrel (ENG) Implant Insertion for Emergency Contraception With Oral Levonorgestrel (LNG) vs Placebo

A Multiple-dose Study of ASP8374, an Immune Checkpoint Inhibitor, as a Single Agent and in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors

Find Trials by Condition in Salt Lake City

A Trial of Setanaxib in Patients With Primary Biliary Cholangitis (PBC) and Liver Stiffness

Clinical Trial Readiness to Solve Barriers to Drug Development in FSHD

A Study to Verify the Clinical Benefit of Aducanumab in Participants With Early Alzheimer's Disease

Carvedilol in Preventing Heart Failure in Childhood Cancer Survivors

MERIDIAN: A Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Adults With Amyotrophic Lateral Sclerosis (ALS)

Efficacy Study of Nivolumab Compared to Ipilimumab in Prevention of Recurrence of Melanoma After Complete Resection of Stage IIIb/c or Stage IV Melanoma

Microfragmented Adipose Tissue Compared to Corticosteroid Injection for the Treatment of Knee Osteoarthritis

Laser Ablation of Abnormal Neurological Tissue Using Robotic NeuroBlate System

DALY II USA/ MB-CART2019.1 for DLBCL

Comparative Study of Conventional MR Images With Synthetically Reconstructed MR Images of the Brain

Treatment of Persistent Atrial Fibrillation With Sphere-9 Catheter and Affera Mapping and Ablation System

A Study to Investigate the Efficacy, Safety, and Tolerability of JNJ-42165279 in Adolescent and Adult Participants With Autism Spectrum Disorder

Predictive Analytics and Clinical Decision Support to Improve PrEP Prescribing

Autologous Adipose-derived Stromal Vascular Fraction for Treatment of Knee Osteoarthritis

Study of REM-422 in Patients With AML or Higher Risk MDS

Long-term Follow-up Study With Darvadstrocel in the Treatment of Complex Perianal Fistula

Safety and Efficacy of GS-100 Gene Therapy in Patients With NGLY1 Deficiency

Harnessing Mobile Technology to Reduce Mental Health Disorders in College Populations