Clinical Trials in Salt Lake City

Showing 4441-4460 of 16,694 trials

Multi-Center Study of ManNAc for GNE Myopathy

NCT04231266

GNE myopathy is a rare genetic muscle disease characterized by progressive muscle atrophy and weakness. The disease is caused by mutations in the gene that encodes the enzyme that initiates and regulates N-acetylneuraminic acid (Neu5Ac) biosynthesis and glycan sialylation. Currently, there is no therapy available for this disease. N-Acetylmannosamine (ManNAc), an orphan drug in development for GNE myopathy, is an uncharged monosaccharide and the first committed precursor in Neu5Ac biosynthesis. In this randomized, double-blind, placebo-controlled trial the efficacy and long-term safety of ManNAc will be evaluated in subjects with GNE myopathy.

GNE Myopathy

Leadiant Biosciences, Inc.54 participantsStarted Apr 2022

Los Angeles, California, United States • Iowa City, Iowa, United States • Kansas City, Kansas, United States +7 more locations

RECRUITING< 1 mile

ColoCare Study - Colorectal Cancer Cohort

NCT02328677

ColoCare is an international prospective cohort study of stage I-IV colorectal cancer patients (ICD-10 C18-C20).

Colorectal Cancer

University of Utah5,000 participantsStarted Mar 2007

Los Angeles, California, United States • Tampa, Florida, United States • St Louis, Missouri, United States +4 more locations

Multi-Center Study of ManNAc for GNE Myopathy

ColoCare Study - Colorectal Cancer Cohort

Find Trials by Condition in Salt Lake City

Beliefs, Attitudes, and Response to Genetic Testing in SarcomaPatients

Comprehensive HHT Outcomes Registry of the United States (CHORUS)

Enfortumab Vedotin and Pembrolizumab vs. Chemotherapy Alone in Untreated Locally Advanced or Metastatic Urothelial Cancer

Testing the Effects of MK-3475 (Pembrolizumab) With or Without the Usual Chemotherapy Treatment for Patients 70 Years of Age and Older With Advanced Non-small Cell Lung Cancer

Reproductive Health Program in Patients With Cancer

A Follow-On Study of Donanemab (LY3002813) With Video Assessments in Participants With Alzheimer's Disease (TRAILBLAZER-EXT)

A Study to Investigate Efficacy and Safety of VTAMA® (Tapinarof) Cream, 1% in Plaque Psoriasis in the Head and Neck Region

PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm

A Study of Unesbulin in Participants With Advanced Leiomyosarcoma (LMS)

A Study of Nivolumab or Placebo in Combination With Docetaxel in Men With Advanced Castration-resistant Prostate Cancer

Investigating Geographic Atrophy Insights (i-GAIN) Natural History Study

Open-Label Study of the CDK4/6 Inhibitor SPH4336 in Subjects With Locally Advanced or Metastatic Liposarcomas

A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease Modifying Anti-rheumatic Drugs or Had Previously Received TNFα Inhibitor Treatment

Cangrelor in Acute Myocardial Infarction: Effectiveness and Outcomes Registry

Shared-Decision Making for Hydroxyurea

Pioglitazone for the Treatment of Alcohol Use Disorder

A Dose-finding Study of CC-90009 in Subjects With Relapsed or Refractory Acute Myeloid Leukemia or Relapsed or Refractory Higher-risk Myelodysplastic Syndromes

Neoadjuvant And Adjuvant Abiraterone Acetate + Apalutamide Prostate Cancer Undergoing Prostatectomy