Clinical Trials in Portland

Showing 1141-1160 of 10,048 trials

Effect of Donor Diabetes and Other Factors on Corneal Transplant Endothelial Cell Loss and Success at 5 Years

NCT07217249

This multi-center clinical trial is designed to assess the association of diabetes in a cornea donor with transplant success and loss of endothelial cells 5 years following Descemet membrane endothelial keratoplasty (DMEK). Study eyes are assigned to receive either a cornea from a donor without diabetes or a cornea from a donor with diabetes in a masked fashion.

Fuchs Endothelial Corneal DystrophyCorneal Endothelial Decompensation

Case Western Reserve University570 participantsStarted Dec 2025

Atlanta, Georgia, United States • Indianapolis, Indiana, United States • Iowa City, Iowa, United States +11 more locations

RECRUITINGPhase 3< 1 mile

Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

NCT03126916

This phase III trial studies iobenguane I-131 or lorlatinib and standard therapy in treating younger patients with newly-diagnosed high-risk neuroblastoma or ganglioneuroblastoma. Radioactive drugs, such as iobenguane I-131, may carry radiation directly to tumor cells and not harm normal cells. Lorlatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving iobenguane I-131 or lorlatinib and standard therapy may work better compared to lorlatinib and standard therapy alone in treating younger patients with neuroblastoma or ganglioneuroblastoma.

GanglioneuroblastomaGanglioneuroblastoma, NodularNeuroblastoma

Children's Oncology Group750 participantsStarted May 2018

Birmingham, Alabama, United States • Phoenix, Arizona, United States • Little Rock, Arkansas, United States +159 more locations

Effect of Donor Diabetes and Other Factors on Corneal Transplant Endothelial Cell Loss and Success at 5 Years

Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

Find Trials by Condition in Portland

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

Mobile Health and Social Media Physical Activity Intervention Among Adolescent and Young Adult Childhood Cancer Survivors, the StepByStep Study

Expanded Access Program for OOS Obe-cel

Trial of Acupuncture for Radiation-Induced Xerostomia in Head and Neck Cancer

Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

Assessing Construction Execution Under Sleep Impairment

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis

A Phase Ⅲ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer

Study to Assess the Effect of Ofatumumab in Treatment Naïve, Very Early RRMS Patients Benchmarked Against Healthy Controls.

Function After Anterior Cervical Discectomy and Fusion Surgery: Timing of Physical Therapy

SMP-3124LP in Adults With Advanced Solid Tumors

Oral N-acetylcysteine for Retinitis Pigmentosa

REFOCUS: A First-in-Human Study of Highly Selective FGFR2 Inhibitor, RLY-4008, in Patients With ICC and Other Advanced Solid Tumors

A Study to Assess the Efficacy and Safety of Weekly Doses of GLM101 in Participants With PMM2-CDG

Study of INKmune in Patients With mCRPC (CaRe Prostate)

Use of CereGate Therapy for Freezing of Gait in PD

Optimized Predictive Treatment In Medications for Unipolar Major Depression (OPTIMUM-D)

Phase 2a Study to Assess the Efficacy,Safety and Tolerability of GIA632 in Adult Participants With Moderate to Severe Atopic Dermatitis