Clinical Trials in Portland

Showing 281-300 of 10,048 trials

Clinical Study of Edwards Cardioband FIT Valve Repair System

NCT03382457

Clinical Study of the Edwards Cardioband FIT Repair System

Edwards Lifesciences75 participantsStarted Jul 2018

Chicago, Illinois, United States • Rochester, Minnesota, United States • Morristown, New Jersey, United States +6 more locations

Active Not RecruitingPhase 2/3< 1 mile

INBRX-106 in Combination With Pembrolizumab in First-line PD-L1 CPS≥20 HNSCC

NCT06295731

This seamless phase 2/3 randomized controlled study will evaluate the efficacy and safety of the hexavalent OX40 agonist antibody INBRX-106 combined with the anti-PD-1 antibody pembrolizumab versus pembrolizumab (+ placebo in phase 3) as first-line treatment for patients with locally advanced recurrent or metastatic head and neck squamous cell carcinoma (R/M HSNSCC) incurable by local therapies, expressing PD-L1 with a combined proportion score (CPS) ≥20.

Head and Neck Squamous Cell Carcinoma (HNSCC)

Inhibrx Biosciences, Inc410 participantsStarted May 2024

Duarte, California, United States • Los Angeles, California, United States • Sacramento, California, United States +84 more locations

Clinical Study of Edwards Cardioband FIT Valve Repair System

INBRX-106 in Combination With Pembrolizumab in First-line PD-L1 CPS≥20 HNSCC

Find Trials by Condition in Portland

Testing the Addition of Immunotherapy Before Surgery for Patients With Sarcomatoid Mesothelioma

A Study to Investigate Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), and Immunogenicity of RO7669330 in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

A Study to Evaluate TAR-210 Versus Intravesical Chemotherapy Treatment in Participants With High Risk Non-Muscle-Invasive Bladder Cancer

Clesrovimab (MK-1654) in Infants and Children at Increased Risk for Severe Respiratory Syncytial Virus (RSV) Disease (MK-1654-007)

A Study of the Efficacy and Safety of Guselkumab in Participants With Moderately to Severely Active Crohn's Disease

Study to Evaluate Safety, Tolerability, and Optimal Dose of Candidate GBM Vaccine VBI-1901 in Recurrent GBM Subjects

A Study of JNJ-80948543, a T-cell Redirecting CD79b x CD20 x CD3 Trispecific Antibody, in Participants With Non-Hodgkin Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL)

A Study of Teclistamab With Other Anticancer Therapies in Participants With Multiple Myeloma

A Study to Learn About the Study Medicine Called PF-08046032 in People With Advanced Cancers

A Safety Study of PF-08046044/SGN-35C in Adults With Advanced Cancers

STrategies for Catheter Ablation of peRsistent Atrial Fibrlllation

CHoice of OptImal transCatheter trEatment for Mitral Insufficiency Registry

A Study to Test if Trevogrumab or Trevogrumab With Garetosmab When Taken With Semaglutide is Safe and How Well They Work in Adult Patients With Obesity for Weight Loss, Fat Loss, and Lean Mass Preservation

ProspeCtive, nOn-randoMized, MulticENter Clinical Evaluation of Edwards Pericardial Bioprostheses With a New Tissue Treatment Platform (COMMENCE)

A Study of Navenibart (STAR-0215) in Participants With Hereditary Angioedema

Long-Term, Open-label Study of Oral Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults With HAE

A Study of Selexipag as Add-On Treatment to Standard of Care in Children With Pulmonary Arterial Hypertension

Vertical Sleeve Gastrectomy and Lifestyle Modification for the Treatment of Non-Alcoholic Steatohepatitis