Clinical Trials in Phoenix

Showing 5761-5780 of 12,606 trials

Electrophysiological Recordings of Deep Brain Stimulation in the Basal Ganglia

NCT03088592

The pathology of Parkinson's disease (PD) and the mechanism of Deep Brain Stimulation surgery (DBS) are not completely understood. The recording data that is used routinely as part of the procedure to map the target structures, however, may be analyzed in order to better understand the neural network dynamics in PD. The purpose of the study is to perform simultaneous neural recordings from sub-cortical structures (e.g. subthalamic nucleus \[STN\] or globus pallidus internus \[GPi\]) and the cerebral cortex. These simultaneous recordings may provide insight in the pathology of PD and the mechanism of DBS. The researchers will also study the effects of anesthesia level on neuron synchronization . Recordings with micro-ECoG grid electrodes in the cortex show improved spatial resolution and these will be used to gain better understanding of cortical network dynamics and the synchronization with subcortical structures.

Parkinson Disease

St. Joseph's Hospital and Medical Center, Phoenix34 participantsStarted Feb 2016

Phoenix, Arizona, United States

UNKNOWNPhase 3< 1 mile

18F-Fluciclovine PET Imaging for Detecting High Grade Glioma Recurrence After Radiochemotherapy

NCT05479136

This study will examine whether positron emission tomography (PET) imaging with fluciclovine can reliably differentiate true progression from pseudoprogression months earlier than the conventional MRI methods.

Grade III or Grade IV Glioma

Nicole Hill30 participantsStarted Aug 2022

Phoenix, Arizona, United States

Electrophysiological Recordings of Deep Brain Stimulation in the Basal Ganglia

18F-Fluciclovine PET Imaging for Detecting High Grade Glioma Recurrence After Radiochemotherapy

Find Trials by Condition in Phoenix

Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Symptomatic Severe Aortic Stenosis in High Risk and Very High Risk Subjects Who Need Aortic Valve Replacement

Safety and Efficacy Continued Access Study of the Medtronic CoreValve® System in the Treatment of Symptomatic Severe Aortic Stenosis in Very High Risk Subjects and High Risk Subjects Who Need Aortic Valve Replacement

Irinotecan Hydrochloride and Temozolomide With Temsirolimus or Dinutuximab in Treating Younger Patients With Refractory or Relapsed Neuroblastoma

Effect of Sotagliflozin on Cardiovascular Events in Participants With Type 2 Diabetes Post Worsening Heart Failure (SOLOIST-WHF Trial)

Treatments Against RA and Effect on FDG-PET/CT

TD-1473 Long-Term Safety (LTS) Ulcerative Colitis (UC) Study

Precision Event Monitoring for Patients With Heart Failure Using HeartLogic

A Study of Recombinant Vaccinia Virus in Combination With Cemiplimab for Renal Cell Carcinoma

Rofecoxib Efficacy and Safety Evaluation Trial in Hemophilic Arthropathy

Blepharospasm Patient Survey for Patients With Blepharospasm

Naloxone Hydrochloride Study for Relief of Pruritus in Patients With MF or SS Forms of CTCL

Brigatinib Before Brain Irradiation Trial (B3i Trial)

Safety and Efficacy of Tenalisib (RP6530) in Combination With Romidepsin in Patients With Relapsed/Refractory T-cell Lymphoma

A Study to Assess the Efficacy and Safety of AKST4290 With Aflibercept in Patients With Newly Diagnosed nAMD

Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Recurrent or Progressive Glioblastoma

Microburst Vagus Nerve Stimulator (VNS) Therapy Feasibility Study

An Investigational Immuno-therapy Trial of Pomalidomide and Low-dose Dexamethasone With or Without Elotuzumab to Treat Refractory and Relapsed and Refractory Multiple Myeloma (ELOQUENT-3)

Implementing an Individualized Pain Plan (IPP) for ED Treatment of VOE's in Sickle Cell Disease