Clinical Trials in North Carolina

Showing 14181-14200 of 17,526 trials

Multiple-dose Regimen Study to Assess Effect of 12 Months of Secukinumab Treatment on Skin Response and Biomarkers in Psoriasis Patients

NCT01537432

This study is designed to evaluate the proportion of patients achieving reversal of chronic plaque psoriasis at week 4 and 12 following multiple doses of secukinumab administered subcutaneously (sc) compared to placebo. Starting from week 13, all patients will receive multiple doses of secukinumab up to week 52 to study long term effects of secukinumab. Clinical endpoints including biomarker assessments, PASI, IGA and DLQI will be compared to better understand, why secukinumab may be effective in psoriasis patients.

Psoriasis, Plaque-type Psoriasis

Novartis Pharmaceuticals36 participantsStarted Jan 2012

Birmingham, Alabama, United States • Pasadena, California, United States • Indianapolis, Indiana, United States +9 more locations

COMPLETEDPhase 331 miles

Study of Taxane/Carboplatin +/- Cetuximab as First-Line Treatment for Patients With Advanced/Metastatic Non-Small Cell Lung Cancer

NCT00112294

The primary purpose of this clinical research study is to learn if patients treated with the combination of Taxane/Carboplatin plus Cetuximab (C/T/C) have a longer progression-free survival than patients treated with Taxane/Carboplatin (T/C) alone. The safety of this treatment will also be studied.

Non-Small-Cell Lung Carcinoma

Eli Lilly and Company755 participantsStarted Dec 2004

Birmingham, Alabama, United States • Mobile, Alabama, United States • Anchorage, Alaska, United States +121 more locations

Multiple-dose Regimen Study to Assess Effect of 12 Months of Secukinumab Treatment on Skin Response and Biomarkers in Psoriasis Patients

Study of Taxane/Carboplatin +/- Cetuximab as First-Line Treatment for Patients With Advanced/Metastatic Non-Small Cell Lung Cancer

Find Trials by Condition in North Carolina

Safety Study of Apixaban in Recent Acute Coronary Syndrome

Efficacy and Safety Study of Gevokizumab to Treat Behcet's Disease Uveitis

A Study in Men With Low Testosterone to Measure the Effects of Testosterone Solution on Testosterone Levels, Sex Drive and Energy

A Study to Evaluate the Safety and Effectiveness of CNTO 888 Administered Intravenously (IV) in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Expanded Treatment Prot of Panobinostat in Combo w/ Bortez and Dex in Pts w/ Relapsed and/or Refractory Multiple Myeloma

Efficacy and Safety of Everolimus in Combination Therapy, in Patients With HER2-overexpressing Metastatic Breast Cancer

Safety and Antiviral Study of ACH-126, 443 (Beta-L-Fd4C) in the Treatment of Adults With HIV Infection and Modestly Detectable Viral Load.

A MultiCenter Study of Combined PEX, Rituximab, and Steroids in Acute Idiopathic Pulmonary Fibrosis Exacerbations

Study Evaluating ACC-001 In Subjects With Mild To Moderate Alzheimer's Disease

Study to Evaluate the Effect of Cetuximab on Corrected QT (QTc) Interval Changes in Patients With Advanced Malignancies From Solid Tumors

Study of Erbitux™ (Cetuximab) in Pediatric Patients With Refractory Solid Tumors

Noninvasive Methods to Monitor Graft Survival in Heart Transplant Patients

Study of GRN163L With Paclitaxel and Carboplatin in Patients With Advanced or Metastatic Non Small Cell Lung Cancer

Safety and Dose Study of GRN163L to Treat Patients With Chronic Lymphoproliferative Disease(CLD)

HT-0712 vs. Placebo in Subjects With Age-Associated Memory Impairment (AAMI)

Coordinating Center for Caregiver Intervention Trial

Imexon for Relapsed Follicular and Aggressive Lymphomas

A Pharmacodynamics Pre-surgical Study of LEE011 in Early Breast Cancer Patients (MONALEESA-1)