Clinical Trials in North Carolina

Showing 10601-10620 of 15,496 trials

Cooperative Lifestyle Programs (CLIP-II)

NCT01547182

The aim is to study the effects of weight loss and weight loss combined with different types of physical activity on changes in physical functioning of older adults who are at-risk for cardiovascular disease.

Cardiovascular DiseaseObesityPhysical Disability

Wake Forest University Health Sciences249 participantsStarted Mar 2012

Kernersville, North Carolina, United States • Winston-Salem, North Carolina, United States • Winston-Salem, North Carolina, United States

COMPLETEDPhase 241 miles

Ganciclovir/Valganciclovir for Prevention of CMV Reactivation in Acute Injury of the Lung and Respiratory Failure

NCT01335932

To evaluate whether administration of ganciclovir reduces serum IL-6 levels (i.e. reduction between baseline and 14 days post-randomization) in immunocompetent adults with severe sepsis or trauma associated respiratory failure. Primary Hypotheses: \- In CMV seropositive adults with severe sepsis or trauma , pulmonary and systemic CMV reactivation amplifies and perpetuates both lung and systemic inflammation mediated through specific cytokines, and contributes to pulmonary injury and multiorgan system failure, AND \- Prevention of CMV reactivation with ganciclovir decreases pulmonary and systemic inflammatory cytokines that are important in the pathogenesis of sepsis and trauma related complications.

Acute Lung InjuryAcute Respiratory Distress SyndromeRespiratory Failure

Fred Hutchinson Cancer Center160 participantsStarted Mar 2011

Denver, Colorado, United States • Chicago, Illinois, United States • Springfield, Massachusetts, United States +11 more locations

Cooperative Lifestyle Programs (CLIP-II)

Ganciclovir/Valganciclovir for Prevention of CMV Reactivation in Acute Injury of the Lung and Respiratory Failure

Find Trials by Condition in North Carolina

Aprepitant in Preventing Nausea and Vomiting in Patients Undergoing Chemotherapy and Radiation Therapy for Pancreatic Cancer

Development and Validation of a Quality of Life Instrument for Actinic Keratosis

Early Provision of Enteral Microlipid and Fish Oil to Infants With Enterostomy

Predicting Acute Compartment Syndrome (PACS)

Supportive Intervention Programs Study

Lifestyle Intervention for Treatment of Diabetes

SF1126 for Patients With Relapsed or Refractory Neuroblastoma

Transcranial Alternating Current Stimulation for Major Depressive Disorder

Transfusion Requirements in Cardiac Surgery III

The POSAtive Study: Study for the Treatment of Positional Obstructive Sleep Apnea

A Study to Evaluate the Effect of Belimumab on Vaccine Responses in Subjects With Systemic Lupus Erythematosus (SLE)

Study to Evaluate the Safety and Immune Response of Two-Doses of Candidate Influenza Vaccine GSK 1557484A in Adults

EINSTEIN Junior Phase II: Oral Rivaroxaban in Young Children With Venous Thrombosis

Everolimus (RAD001) for Children With Chemotherapy-Refractory Progressive or Recurrent Low-Grade Gliomas

US-licensed Combined Vaccine Against Tetanus & Diphtheria, Given With US-licensed Vaccine Against Meningococcal Disease

Pharmacokinetics, Safety, and Efficacy of Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Disoproxil Fumarate Single Tablet Regimen (STR) in Adolescents

Liposomal Doxorubicin Followed By Bexarotene in Treating Patients With Cutaneous T-Cell Lymphoma

Automated Screen for Fetal Aneuploidy