Clinical Trials in North Carolina

Showing 10201-10220 of 15,496 trials

A Dose Titration Study of CPC-201 in Patients With Dementia of Alzheimer's Type

NCT02549196

This is a Phase II, ascending dose study of CPC-201 in patients with dementia of Alzheimer's type to determine the optimal dose titration schedule.

Dementia of Alzheimer's Type

Chase Pharmaceuticals Corporation, an affiliate of Allergan plc28 participantsStarted Oct 2015

Deerfield Beach, Florida, United States • Miami, Florida, United States • West Palm Beach, Florida, United States +1 more locations

TERMINATED46 miles

Assessing Ocular Hemodynamic Response to Surgical Intervention in Glaucoma

NCT02891317

The purpose of this study is to assess how surgical interventions in glaucoma affect 24-hour intraocular pressure, 24-hour ocular perfusion pressure, optic nerve blood flow, and retinal oxygen saturation.

Primary Open Angle GlaucomaLow Tension GlaucomaCataract+1 more

University of North Carolina, Chapel Hill2 participantsStarted May 2017

Chapel Hill, North Carolina, United States

TERMINATEDPhase 146 miles

A Study of PF-05082566 In Combination With Mogamulizumab In Patients With Advanced Solid Tumors

NCT02444793

This study is a Phase 1b, open label, multi center, multi-dose trial designed to estimate the maximum tolerated dose (MTD) and select the recommended dose for phase 2 (RP2D) investigations of PF- 05082566 in combination with KW-0761 (mogamulizumab) in patients with advanced solid tumors. Once the MTD of PF-05082566 administered in combination with KW-0761 is estimated (dose finding), one or more expansion cohorts of patients with selected advanced solid tumors (dose-expansion ) will be enrolled to further characterize the combination in term of safety profile, anti tumor activity, pharmacokinetics, pharmacodynamics and biomarkers modulation.

Advanced/Metastatic Solid Tumors

Pfizer24 participantsStarted May 2015

La Jolla, California, United States • La Jolla, California, United States • La Jolla, California, United States +18 more locations

A Dose Titration Study of CPC-201 in Patients With Dementia of Alzheimer's Type

Assessing Ocular Hemodynamic Response to Surgical Intervention in Glaucoma

A Study of PF-05082566 In Combination With Mogamulizumab In Patients With Advanced Solid Tumors

Find Trials by Condition in North Carolina

Clinical Study of Macitentan in Patients With Pulmonary Arterial Hypertension to Psychometrically Validate the PAH-SYMPACT Instrument

An Open-Label Extension Study to Evaluate the Safety of the ForSight VISION5 Product

Comparative Investigation of Low Molecular Weight (LMW) Heparin/Edoxaban Tosylate (DU176b) Versus (LMW) Heparin/Warfarin in the Treatment of Symptomatic Deep-Vein Blood Clots and/or Lung Blood Clots. (The Edoxaban Hokusai-VTE Study).

Safety and Dose Ranging Study of Samalizumab to Treat Relapsing or Refractory CLL or MM

Evaluation of a Single Vaccination With One of Three Ascending Dose Levels of a 4-Antigen Staphylococcus Aureus Vaccine (SA4Ag) in Healthy Adults Aged 18 to <65 Years

Evaluation of a Single Vaccination of One of Three Ascending Dose Levels of a 4-Antigen Staphylococcus Aureus Vaccine (SA4Ag) and a Single Dose Level of a 3-Antigen Staphylococcus Aureus Vaccine (SA3Ag) in Healthy Adults Aged 65 to <86 Years

Long-term Follow-up Study of Subjects Who Completed Clinical Studies 755.1100_FA, 810.1100_FA, or 1064.1100_FA

Safety and Efficacy of Sofosbuvir/Velpatasvir/Voxilaprevir and Sofosbuvir/Velpatasvir in Adults With Chronic HCV Infection Who Have Not Previously Received Treatment With Direct-Acting Antiviral Therapy

An Open-Label Safety Study of API 31510 in a Topical Cream for in Situ Cutaneous Squamous Cell Carcinoma (SCCIS)

Post Approval Study of the TS Feature With the 530G Pump System Supplemented With Commercial Patient Data

Tolerability, Safety, and Feasibility of Naloxegol in Patients With Cancer and OIC (Opioid Induced Constipation)

Irrigated Ablation System Evaluation for Atrial Fibrillation (AF)

VL-2397 Compared to Standard First-Line Treatment for Invasive Aspergillosis (IA) in Adults

Effect of Intramyocardial Injection of Mesenchymal Precursor Cells on Heart Function in People Receiving an LVAD

Safety and Efficacy Trial of DNA Vaccines to Treat Genital Herpes in Adults

Assessment of Diagnostic Accuracy and Performance of Digital Breast Tomosynthesis Compared to Mammography (ADAPT)

Fresolimumab and Radiotherapy in Metastatic Breast Cancer