Clinical Trials in North Carolina

Showing 801-820 of 17,526 trials

Randomized Trial of Sedative Choice for Intubation

NCT05277896

Among critically ill adults undergoing emergency tracheal intubation, one in five experience hypotension, cardiac arrest, or death. The sedatives used to rapidly induce anesthesia for emergency tracheal intubation have been hypothesized to effect cardiovascular complications and patient outcomes, but the optimal sedative medication for intubation of critically ill adults remains unknown. Ketamine and etomidate are the two most commonly used sedatives during intubation of critically ill adults. Data from a randomized clinical trial are urgently needed to determine the effect of ketamine versus etomidate on cardiovascular complications and clinical outcomes of emergency tracheal intubation.

Acute Respiratory Failure

Vanderbilt University Medical Center2,367 participantsStarted Apr 2022

Birmingham, Alabama, United States • Aurora, Colorado, United States • Denver, Colorado, United States +3 more locations

TERMINATEDEARLY Phase 141 miles

Study of Combined Decompressive Spine Radiosurgery and Pembrolizumab

NCT05204290

The purpose of this research study is to find out what effects (good and bad) Pembrolizumab and radiosurgery have on participants with high-grade epidural disease of the spine.

Epidural Spinal TumorsCancer

Wake Forest University Health Sciences1 participantsStarted Mar 2022

Winston-Salem, North Carolina, United States

Randomized Trial of Sedative Choice for Intubation

Study of Combined Decompressive Spine Radiosurgery and Pembrolizumab

Find Trials by Condition in North Carolina

Glioma Modified Atkins-based Diet in Patients With Glioblastoma

Identifying Challenges to Healthy Aging in Persons With Human Immunodeficiency Virus (HIV) Age 50 and Older

A Study of Enfortumab Vedotin Alone or With Other Therapies for Treatment of Urothelial Cancer

A Study of Tinengotinib (TT-00420) in Combination With Standard Treatments in People With Prostate Cancer

A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis

A Global, Multicenter Study to Assess Maternal, Fetal and Infant Outcomes of Exposure to Palynziq® (Pegvaliase) During Pregnancy and Breastfeeding

Study to Evaluate ARO-APOC3 in Adults With Severe Hypertriglyceridemia

Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer

Study of Efficacy and Safety of Secukinumab in Participants With Moderate-severe Rotator Cuff Tendinopathy

Observational Study of Pediatric Acute Kidney Injury, Risk Factors and Outcomes

Study of DS-1062a in Advanced or Metastatic Non-small Cell Lung Cancer With Actionable Genomic Alterations (TROPION-Lung05)

An Efficacy and Safety Study of Cofetuzumab Pelidotin in Participants With PTK7-Expressing, Recurrent Non-Small Cell Lung Cancer

A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (CSU)

A Multicenter Patient Registry on Outcomes From Cryoanalgesia of the Intercostal Nerves

Study to Evaluate Xtresse Serum in Individuals With Thinning Hair

MicroVention, Inc. Flow Re-Direction Endoluminal Device X (FRED™ X™) Post-Approval Study

Open Nipple Sparing Mastectomy (NSM)

Living WELL: A Web-Based Program for Ovarian Cancer Survivors