Clinical Trials in North Carolina

Showing 7681-7700 of 15,496 trials

Role of Polyunsaturated Fatty Acids (PUFA)-Gene Interactions in Heath Disparities

NCT02962128

A randomized, clinical trial to provide the first comprehensive investigation of the role of fatty acid desaturate (FADS) genetic determinants on PUFA biosynthesis and metabolism as well as levels of inflammatory markers in a controlled dietary environment using two (low and high linoleic acid) parallel diets.

Fatty Acid-Gene Interactions

Wake Forest University Health Sciences80 participantsStarted Nov 2016

Winston-Salem, North Carolina, United States

COMPLETEDPhase 241 miles

Minocycline Hydrochloride in Reducing Chemotherapy-Induced Peripheral Neuropathy and Acute Pain in Patients With Breast Cancer Undergoing Treatment With Paclitaxel

NCT02297412

This randomized pilot trial studies how well minocycline hydrochloride works in reducing chemotherapy-induced peripheral neuropathy and acute pain in patients with breast cancer undergoing treatment with paclitaxel. Drugs used in chemotherapy, such as paclitaxel, may cause damage to nerves that result in aches, pains, and tingling or numbness of fingers and toes. Minocycline hydrochloride may help lessen nerve damage from paclitaxel and improve the quality of life in breast cancer patients.

Acute PainBreast CarcinomaPeripheral Neuropathy

Academic and Community Cancer Research United47 participantsStarted Nov 2014

Pismo Beach, California, United States • Normal, Illinois, United States • Urbana, Illinois, United States +9 more locations

Role of Polyunsaturated Fatty Acids (PUFA)-Gene Interactions in Heath Disparities

Minocycline Hydrochloride in Reducing Chemotherapy-Induced Peripheral Neuropathy and Acute Pain in Patients With Breast Cancer Undergoing Treatment With Paclitaxel

Find Trials by Condition in North Carolina

Study of Azeliragon in Patients With Mild Alzheimer's Disease and Impaired Glucose Tolerance

Study to Evaluate Eflornithine + Lomustine vs Lomustine in Recurrent Anaplastic Astrocytoma (AA) Patients

Study to Evaluate the Efficacy and Safety of Filgotinib in Adults With Active Noninfectious Uveitis

Combination Chemotherapy in Treating Young Patients With Down Syndrome and Acute Myeloid Leukemia or Myelodysplastic Syndromes

Euglycemia After Antenatal Late Preterm Steroids, the E-ALPS Study

A Phase 2 Study of CIM331 for Atopic Dermatitis Patients

Efficacy and Safety Comparison of Albuterol Spiromax® and ProAir® Hydrofluoroalkane (HFA) in Pediatric Patients

A Study of Pembrolizumab Plus Epacadostat With Platinum-based Chemotherapy Versus Pembrolizumab Plus Platinum-based Chemotherapy Plus Placebo in Metastatic Non-Small Cell Lung Cancer (KEYNOTE-715-06/ECHO-306-06)

Study of TV-1106 in Growth Hormone-Deficient Adults

A Multi-Center Trial to Study Acute Liver Failure in Adults

UNLOCKED: A Phase 2, Open-label Trial With KB195 in Subjects With a Urea Cycle Disorder

An Investigational Immuno-Therapy Study of Experimental Medication BMS-986178 by Itself or in Combination With Nivolumab and/or Ipilimumab in Participants With Solid Cancers That Are Advanced or Have Spread

Safety Evaluation of the Hybrid Closed Loop (HCL) System in Pediatric Subjects With Type 1 Diabetes

IPH5401 (Anti-C5aR) in Combination With Durvalumab in Patients With Advanced Solid Tumors

Phase I/Ib Study of NIS793 in Combination With PDR001 in Patients With Advanced Malignancies.

Safety and Efficacy Study of Adult Human Mesenchymal Stem Cells to Treat Acute Graft Versus Host Disease (GVHD)

Tamoxifen for Progressive Transitional Cell Carcinoma Following Previous Chemotherapy Treatment

Awareness, Care & Treatment In Obesity Management - An International Observation Among Teens (ACTION Teens)