Clinical Trials in North Carolina

Showing 7221-7240 of 15,496 trials

Prognosticating Outcomes and Nudging Decisions With Electronic Records in the ICU Trial

NCT03139838

This is a pragmatic, stepped-wedge, cluster randomized trial testing the real-world effectiveness of two different electronic health record (EHR) behavioral interventions in improving a number of patient- and family-centered processes and outcomes of care among seriously ill hospitalized patients. The investigators hypothesize that outcomes can be improved without raising costs by requiring intensive care unit clinicians to (i) document a prognostic estimate and (ii) provide a justification if they choose not to offer patients the option of comfort-oriented care. To test this hypothesis the investigators will conduct a 33-month trial at 17 intensive care units in 10 hospitals using the same Cerner EHR within Atrium Health System.

Critical Illness

University of Pennsylvania3,500 participantsStarted Feb 2018

Albemarle, North Carolina, United States • Charlotte, North Carolina, United States • Charlotte, North Carolina, United States +7 more locations

COMPLETEDPhase 339 miles

Efficacy and Safety of Brolucizumab vs Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema

NCT03917472

The purpose of this study was to evaluate the efficacy and safety of brolucizumab vs. aflibercept in the treatment of patients with visual impairment due to diabetic macular edema (DME).

Diabetic Macular Edema

Novartis Pharmaceuticals517 participantsStarted Jul 2019

Phoenix, Arizona, United States • Phoenix, Arizona, United States • Tucson, Arizona, United States +89 more locations

Prognosticating Outcomes and Nudging Decisions With Electronic Records in the ICU Trial

Efficacy and Safety of Brolucizumab vs Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema

Find Trials by Condition in North Carolina

FGF23 and Angiotensin-(1-7) in Hypophosphatemia (GAP)

Study to Assess the Effectiveness of AboBoNT-A Injections for Adult Lower Limb Spasticity in a Real Life Cohort

Sorafenib Tosylate With or Without Doxorubicin Hydrochloride in Treating Patients With Locally Advanced or Metastatic Liver Cancer

Biomarkers in Patients With Rectal Cancer Undergoing Chemotherapy and Radiation Therapy

Rare Genetic Disorders of the Breathing Airways

Study of Nivolumab (BMS-936558) vs. Everolimus in Pre-Treated Advanced or Metastatic Clear-cell Renal Cell Carcinoma (CheckMate 025)

Trial to Evaluate Efficacy and Safety of Lenabasum in Dermatomyositis

A Global Study Comparing Risankizumab to Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

A Study of LY3561774 in Participants With Dyslipidemia

Study of Tisagenlecleucel in Combination With Pembrolizumab in r/r Diffuse Large B-cell Lymphoma Patients

Phase ll Study of Pirfenidone in Patients With RAILD (TRAIL1)

Transdisciplinary Versus Usual Care for Type1 Diabetes in Adolescence

Salivary Profiling in Infants Treated for Suspected Sepsis: The SPITSS Study

Safety, Pharmacokinetics and Efficacy of ARQ-151 Cream in Adults With Mild to Moderate Chronic Plaque Psoriasis

Dalteparin and Sunitinib Malate as First-Line Therapy in Treating Patients With Kidney Cancer That is Metastatic or Cannot Be Removed by Surgery

Treatment for COVID-19 in High-Risk Adult Outpatients

A Study of Obinutuzumab (RO5072759) Plus Chemotherapy in Comparison With Rituximab Plus Chemotherapy Followed by Obinutuzumab or Rituximab Maintenance in Patients With Untreated Advanced Indolent Non-Hodgkin's Lymphoma (GALLIUM)

Safety, Tolerability and Efficacy of Nidufexor in Patients With Diabetic Nephropathy