Clinical Trials in North Carolina

Showing 5821-5840 of 20,428 trials

BATwire Implant Kit

NCT04600791

The purpose of this clinical investigation is to develop valid scientific evidence for the safety and effectiveness of the Barostim System delivered by the BATwire Implant Kit (BATwire Kit) in subjects with heart failure. Subjects may be enrolled if they meet the FDA approved PMA indication for use for the Barostim NEO or Barostim NEO2 device: Subjects who remain symptomatic despite treatment with guideline-directed medical therapy, are NYHA Class III or Class II (who had a recent history of Class III), have a left ventricular ejection fraction ≤ 35%, a NT-proBNP \< 1600 pg/ml and excludes patients indicated for Cardiac Resynchronization Therapy (CRT) according to AHA/ACC/ESC guidelines.

Heart Failure

CVRx, Inc.93 participantsStarted Jan 2021

Mesa, Arizona, United States • Scottsdale, Arizona, United States • Orlando, Florida, United States +7 more locations

COMPLETEDNA46 miles

enCompass Carolina: A Social Support and Coaching Program for Cancer Caregivers

NCT05828927

This study explores the feasibility, acceptability, and preliminary efficacy of a social support intervention in cancer caregivers who live in rural communities. Cancer caregivers need support, especially when they live at a distance from healthcare centers. enCompass Carolina is a social support intervention, that supports caregivers by helping them find and use new sources of support. The purpose of this study is to test and receive feedback about the program.

Cancer

UNC Lineberger Comprehensive Cancer Center111 participantsStarted May 2023

Chapel Hill, North Carolina, United States

BATwire Implant Kit

enCompass Carolina: A Social Support and Coaching Program for Cancer Caregivers

Find Trials by Condition in North Carolina

Ultra Hypo-fractionated Adjuvant Whole Breast Radiation Therapy With Simultaneous Integrated Boost for Early-Stage Breast Cancer (H-ASSIST)

Retrospective Chart Review of First-time Opsumit® (Macitentan) Users in the United States

A Study to Evaluate Whether Macitentan is an Effective and Safe Treatment for Patients With Heart Failure With Preserved Ejection Fraction and Pulmonary Vascular Disease

Clinical Study to Assess the Long-term Safety and Tolerability of ACT 064992 in Patients With Symptomatic Pulmonary Arterial Hypertension

A Study of Zanubrutinib (BGB-3111) Versus Ibrutinib in Participants With Relapsed/Refractory Chronic Lymphocytic Leukemia

Pharmacokinetic, Pharmacodynamic, Safety, and Efficacy Study of Rivaroxaban for Thromboprophylaxis in Pediatric Participants 2 to 8 Years of Age After the Fontan Procedure

To Evaluate the Efficacy, Safety, and Tolerability of BBT-877 in Patients With IPF

Study to Evaluate the Safety and Efficacy of SPR001 in Subjects With Classic Congenital Adrenal Hyperplasia

Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low Weight Infants

A Study of Real-life Current Standards of Care in Patients With Relapsed and/or Refractory Multiple Myeloma Who Received at Least 3 Prior Lines of Therapy Including Proteasome Inhibitor (PI), Immunomodulatory Drug (IMID), and Cluster of Differentiation 38 (CD38) Monoclonal Antibody Treatment

Clinical Study Assessing the Efficacy and Safety of Macitentan in Fontan-palliated Subjects

Safety, Tolerability, and Pharmacokinetics of Oral Treprostinil in Pediatric PAH Patients Aged 7 to 17 Years

Daratumumab Retreatment in Participants With Multiple Myeloma Who Have Been Previously Treated With Daratumumab

A Study of JNJ-70033093 (BMS-986177) Versus Subcutaneous Enoxaparin in Participants Undergoing Elective Total Knee Replacement Surgery

A Study of Guselkumab in Participants With Active Lupus Nephritis

Study of AIC100 CAR T Cells in Relapsed/Refractory Thyroid Cancer

Study to Estimate How Common it is to Have Genetic Variants Associated With NAFLD

Clinical Study to Assess the Safety, Tolerability and Efficacy of Macitentan in Subjects With Inoperable Chronic Thromboembolic Pulmonary Hypertension