Clinical Trials in North Carolina

Showing 4941-4960 of 15,496 trials

Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma

NCT02101905

This pilot phase I clinical trial studies how well lapatinib ditosylate before surgery works in treating patients with high-grade glioma that has come back after a period of time during which the tumor could not be detected. Lapatinib ditosylate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Anaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Oligodendroglioma+4 more

National Cancer Institute (NCI)29 participantsStarted Nov 2016

Los Angeles, California, United States • Baltimore, Maryland, United States • Boston, Massachusetts, United States +9 more locations

COMPLETEDPhase 246 miles

Pembrolizumab + Radiation for Locally Adv SCC of the Head and Neck (SCCHN) Not Eligible Cisplatin

NCT02609503

This study is being done to evaluate the efficacy of Pembrolizumab, concomitant with and following standard of care definitive radiation, for locally advanced squamous cell carcinoma of the head and neck patients who are not good candidates for Cisplatin.

Head and Neck Cancer

UNC Lineberger Comprehensive Cancer Center29 participantsStarted May 2016

Baltimore, Maryland, United States • Chapel Hill, North Carolina, United States • Philadelphia, Pennsylvania, United States

Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma

Pembrolizumab + Radiation for Locally Adv SCC of the Head and Neck (SCCHN) Not Eligible Cisplatin

Find Trials by Condition in North Carolina

Preemie Hypothermia for Neonatal Encephalopathy

Study of MT-6402 in Subjects With Advanced Solid Cancer That Expresses PD-L1

The Sanderson Study: A Case Control Study for the Development of Multiomics Blood Tests for Cancer Screening

A Study to Test Whether Taking BI 1358894 for 8 Weeks Helps Adults With Post-traumatic Stress Disorder

Ganitumab in Locally Advanced Unresectable Adenocarcinoma of the Pancreas

StrataMGT in the Reduction of Vulvar Lichen Sclerosus (LS) Symptoms

Study of Nab-Paclitaxel and Gemcitabine With or Without SBP-101 in Pancreatic Cancer

Memory Retrieval and Encoding Investigated by Neural Stimulation

Efficacy, Safety, Pharmacodynamic, and Pharmacokinetics Study of Olipudase Alfa in Patients With Acid Sphingomyelinase Deficiency

Lumateperone for the Prevention of Relapse in Patients With Schizophrenia

North American Prodromal Synucleinopathy Consortium

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK2798745 in Participants With Diabetic Macular Edema

A Study to Evaluate Pegsitacianine, an Intraoperative Fluorescence Imaging Agent for the Detection of Lung Malignancies

Temozolomide (TMZ) in Advanced Succinate Dehydrogenase (SDH)-Mutant/Deficient Gastrointestinal Stromal Tumor (GIST)

A Phase 1, Dose Escalation Study to Assess the Safety and Tolerability of ASP9853 With Either Docetaxel or Paclitaxel in Patients With Advanced Non-hematologic Malignancies

EnSite Precision Observational Study

Study to Evaluate the Safety, Tolerability,Pharmacokinetics, and Antitumor Activity of a Thorium-227 Labeled Antibody-chelator Conjugate Alone and in Combination With Darolutamide, in Patients With Metastatic Castration Resistant Prostate Cancer

ART-Pro: Clinical Trial Evaluating Biparametric MRI and Advanced, Quantitative Diffusion MRI for Detection of Prostate Cancer