Clinical Trials in North Carolina

Showing 4121-4140 of 17,526 trials

Study of Nasal Insulin to Fight Forgetfulness - Short-Acting Insulin Aspart

NCT02462161

This pilot clinical trial will examine the effects of intranasal insulin aspart on cognition, daily function, blood and cerebral spinal fluid markers of Alzheimer's disease, and amyloid deposition in the brain. Participants will be randomly assigned to receive insulin aspart or placebo during a 12-week treatment period.

Alzheimer's DiseaseMild Cognitive Impairment

Wake Forest University Health Sciences24 participantsStarted Mar 2015

Winston-Salem, North Carolina, United States

COMPLETEDNA41 miles

Effect of a Modified Ketogenic-Mediterranean Diet on Alzheimer's Disease

NCT02984540

The purpose of the BEAM study is to compare the effects of a low-carbohydrate diet and a lowfat diet for adults with mild memory loss and adults with pre-diabetes. The data collected will help determine changes in cognitive function, brain structure and function, and levels of certain proteins and hormones in body fluids.

Mild Cognitive ImpairmentInsulin Resistance

Wake Forest University Health Sciences25 participantsStarted Feb 2015

Winston-Salem, North Carolina, United States

TERMINATEDPhase 357 miles

Safety and Efficacy of Hectorol in Pediatric Patients With Chronic Kidney Disease Stage 3 and 4 With Secondary Hyperparathyroidism Not Yet on Dialysis

NCT02859896

Primary Objective: Evaluate the effect of Hectorol® capsules in reducing elevated levels of intact parathyroid hormone (iPTH). Secondary Objectives: * Evaluate the safety profile of Hectorol® capsules versus Rocaltrol® (calcitriol) capsules. * Determine the pharmacokinetic profile of 1,25-dihydroxyvitamin D2 after administration of Hectorol®.

Secondary Hyperparathyroidism-Chronic Kidney Disease

Sanofi21 participantsStarted Jan 2017

Birmingham, Alabama, United States • Los Angeles, California, United States • Sacramento, California, United States +20 more locations

Study of Nasal Insulin to Fight Forgetfulness - Short-Acting Insulin Aspart

Effect of a Modified Ketogenic-Mediterranean Diet on Alzheimer's Disease

Safety and Efficacy of Hectorol in Pediatric Patients With Chronic Kidney Disease Stage 3 and 4 With Secondary Hyperparathyroidism Not Yet on Dialysis

Find Trials by Condition in North Carolina

Clinical Performance Evaluation of T-TAS®01 HD Chip

Web-based Pain Coping Skills Training for Breast Cancer Survivors With AI-Associated Arthralgia

Study of Obeldesivir to Treat Nonhospitalized Adults With Acute Respiratory Syncytial Virus (RSV) Infection

Pembrolizumab (MK-3475) Plus Epacadostat vs Standard of Care in mRCC (KEYNOTE-679/ECHO-302)

A Study to Evaluate Safety and Tolerability of CVL-231 (Emraclidine) in Adult Participants With Schizophrenia

Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Follicular Lymphoma

TTX-030 in Combination With Immunotherapy and/or Chemotherapy in Subjects With Advanced Cancers

Development and Validation of Harbinger Health Test for Early Cancer Detection

A Long-term Follow-up Study of Patients Who Received VOR33

Donor-Derived Anti-CD33 CAR T Cell Therapy (VCAR33) in Patients With Relapsed or Refractory AML After Allogeneic Hematopoietic Cell Transplant

A Study of Sequential Therapy With Daplusiran/Tomligisiran (DAP/TOM) Followed by Bepirovirsen in Participants Living With Chronic Hepatitis B (CHB)

A Study of LY3372689 to Assess the Safety, Tolerability, and Efficacy in Participants With Alzheimer's Disease

A Study to Learn About the Study Medicine (Nirmatrelvir Plus Ritonavir) in Pregnant Women With COVID-19

Prospective, Open-label, Non-significant Risk, Multicenter Study Comparing the Polyp Detection of the Study Device to That of the Colonoscopy Reference

A Study of Meaning-Centered Psychotherapy for Caregivers to People With Cancer

A Rapid Diagnostic of Risk in Hospitalized Patients Using Machine Learning

TURN-IT FOG: Improving Turning and Freezing of Gait in People With PD