Clinical Trials in North Carolina

Showing 3661-3680 of 17,526 trials

Study to Evaluate SAGE-547 Injection as Adjunctive Therapy for the Treatment of Super-Refractory Status Epilepticus

NCT02052739

The purpose of this study is to evaluate the safety and tolerability of SAGE-547 in participants in super-refractory status epilepticus (SRSE).

Super-refractory Status Epilepticus

Supernus Pharmaceuticals, Inc.25 participantsStarted Mar 2014

Birmingham, Alabama, United States • Sarasota, Florida, United States • Chicago, Illinois, United States +14 more locations

COMPLETEDPhase 246 miles

A Study to Evaluate SAGE-547 in Participants With Severe Postpartum Depression

NCT02614547

This is a multicenter, randomized, double-blind, parallel-group, placebo-controlled study of the efficacy, safety, and pharmacokinetics of SAGE-547 Injection in adult female participants diagnosed with severe postpartum depression.

Severe Postpartum Depression

Supernus Pharmaceuticals, Inc.21 participantsStarted Dec 2015

Atlanta, Georgia, United States • Worcester, Massachusetts, United States • Chapel Hill, North Carolina, United States +1 more locations

Study to Evaluate SAGE-547 Injection as Adjunctive Therapy for the Treatment of Super-Refractory Status Epilepticus

A Study to Evaluate SAGE-547 in Participants With Severe Postpartum Depression

Find Trials by Condition in North Carolina

28-Day Study of SAGE-718 on Functioning Capacity in Participants With Huntington's Disease

A Study to Evaluate the Effect of SAGE-718 on Cognitive Function in Participants With Huntington's Disease (HD)

A First-in-human Study Using BDC-1001 as a Single Agent and in Combination With Nivolumab in Advanced HER2-Expressing Solid Tumors

Cross-Seal Closure Device IDE Trial - Study of the Cross-SealTM Suture-Mediated Vascular Closure Device System

Safety Study of a Vaccine to Help Protect Against Lyme Disease in Healthy Children

A Dose-Range Study of Aleniglipron (GSBR-1290) in Participants Living With Obesity or Overweight With at Least One Weight-related Comorbidity

A Study in Adults to Investigate the Impact of Mild, Moderate, and Severe Hepatic Impairment on Pharmacokinetics of Venglustat Compared to Participants With Normal Hepatic Function

Tailored vs. Anatomical Ablation Strategy for Persistent Atrial Fibrillation

PRO 140 in Treatment-Experienced HIV-1 Subjects

NANT 2015-02: A Phase 1 Study of Lorlatinib (PF-06463922)

Treatment Monitoring in Autism Spectrum Disorder (ASD) in Children

DFC 004 Biomarkers for Active Diabetic Foot Ulcers

Veliparib and Topotecan Hydrochloride in Treating Patients With Solid Tumors, Relapsed or Refractory Ovarian Cancer, or Primary Peritoneal Cancer

A Study Evaluating Efficacy and Safety of Multiple Treatment Combinations in Patients With Locally Advanced Squamous Cell Carcinoma of the Head and Neck (Morpheus-Head and Neck Cancer)

A Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Participants With Ichthyosis

Study to Assess the Safety and Immunogenicity of Monovalent mRNA NA Vaccine in Adult Participants 18 Years of Age and Older

Pharmacodynamic EffIcacy and Clinical Benefit of AT 007 in Patients With Sorbitol Dehydrogenase (SORD) Deficiency

A Study to Evaluate the Safety and Tolerability of SAGE-718 in Participants With Parkinson's Disease Mild Cognitive Impairment (PD-MCI)