Clinical Trials in North Carolina

Showing 2701-2720 of 20,428 trials

Study to Assess Safety, Efficacy, and Cellular Kinetics of YTB323 in Generalized Myasthenia Gravis

NCT06704269

This is a phase I/II study to assess safety, efficacy, and cellular kinetics of YTB323 in participants with treatment-resistant generalized myasthenia gravis. YTB323 is a Biological CAR-T cell therapy.

Generalized Myasthenia Gravis

Novartis Pharmaceuticals15 participantsStarted Apr 2025

Orange, California, United States • Winston-Salem, North Carolina, United States • Houston, Texas, United States +7 more locations

RECRUITINGNA41 miles

I-DECIDE After Bronchiolitis Hospitalization

NCT07243652

Although automatic follow-up is a nearly universal practice, research has shown that these visits are often unnecessary after hospitalizations caused by bronchiolitis. Despite endorsement by national pediatric authorities, robust evidence, and family enthusiasm for as-needed (PRN) follow-up, it remains substantially underutilized for children hospitalized for bronchiolitis. The goal of I-DECIDE is to compare the effects of two multi-component implementation strategies, both of which aim to (a) increase PRN follow-up prescribing by hospitalists (physicians who care for hospitalized children) and (b) decrease unnecessary follow-up visit attendance by families.

Bronchiolitis Acute

Seattle Children's Hospital2,700 participantsStarted Nov 2025

Birmingham, Alabama, United States • Glendale, Arizona, United States • Phoenix, Arizona, United States +53 more locations

Study to Assess Safety, Efficacy, and Cellular Kinetics of YTB323 in Generalized Myasthenia Gravis

I-DECIDE After Bronchiolitis Hospitalization

Find Trials by Condition in North Carolina

Single Versus Dual Implant Fixation of Distal Femur Fractures

A Study of LY3540378 in Participants With Worsening Chronic Heart Failure With Preserved Ejection Fraction (HFpEF)

Building Relationship, Improving Dialogue, and Growing Empathy (BRIDGE): An Intervention to Support Decision Making for Critically Ill Children

A Study of Ripretinib vs Sunitinib in Advanced GIST Patients After Treatment With Imatinib

A Safety and Efficacy Study of HCB101, Fc-fusion Protein Targeting SIRPα-CD47 Pathway, in Solid or Hematological Tumors

Efficacy and Safety of MK-8189 in Participants With an Acute Episode of Schizophrenia (MK-8189-008)

A Post-Authorisation Safety Study (PASS) of Patients Treated With Lonapegsomatropin

Efficacy and Safety Study of First-line Treatment With Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Women With Persistent, Recurrent, or Metastatic Cervical Cancer (MK-3475-826/KEYNOTE-826)

A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

An Investigational Study of BG-89894 Tablets in Participants With Advanced Solid Tumors

Safety and Efficacy Study of Pemetrexed + Platinum Chemotherapy + Pembrolizumab (MK-3475) With or Without Lenvatinib (MK-7902/E7080) as First-line Intervention in Adults With Metastatic Nonsquamous Non-small Cell Lung Cancer (MK-7902-006/E7080-G000-315/LEAP-006)

Elotuzumab in Immunoglobulin G4-Related Disease (IgG4-RD)

Rate of Progression in USH2A-related Retinal Degeneration

Phase Ib/II of TG4001 and Avelumab in HPV16 Positive R/M Cancers

Study Evaluating the Safety and Efficacy of RAP-219 in Adult Participants With Refractory Focal Epilepsy

Hybrid Effectiveness-Implementation Trial to Integrate Precision Skin Cancer Risk Feedback in FQHCs

A Novel Multiplex ELISA Assay for Evaluating Patients With Gross Hematuria for Bladder Cancer

A Study of EBC-129 in Advanced Solid Tumours