Clinical Trials in North Carolina

Showing 2221-2240 of 20,428 trials

Optimization of Postoperative Bowel Habits

NCT06335797

Project is a trial, in which women undergoing vaginal surgery for pelvic organ prolapse will be randomized 1:1 to a postoperative bowel regimen of either oral senna or rectal bisacodyl suppository.

Constipation

Wake Forest University Health Sciences88 participantsStarted Oct 2024

Winston-Salem, North Carolina, United States

RECRUITINGNA41 miles

Autologous Muscle Fiber Fragment Injections

NCT05396456

To regenerate functional anal sphincter muscle using muscle fiber fragments that contain muscle precursor cells (MPCs)

Fecal Incontinence

Wake Forest University Health Sciences10 participantsStarted Jan 2023

Winston-Salem, North Carolina, United States

RECRUITINGPhase 457 miles

Sparsentan in Posttransplant Immunoglobulin A Nephropathy or Focal Segmental Glomerulosclerosis

NCT07219121

To evaluate the safety and efficacy of sparsentan tablets for the treatment of patients with proteinuria after kidney transplantation with once-daily dosing for 36 weeks.

ProteinuriaImmunoglobulin A (IgA) NephropathyFocal Segmental Glomerulosclerosis+1 more

Travere Therapeutics, Inc.20 participantsStarted Oct 2025

Birmingham, Alabama, United States • New York, New York, United States • Morrisville, North Carolina, United States +6 more locations

Optimization of Postoperative Bowel Habits

Autologous Muscle Fiber Fragment Injections

Sparsentan in Posttransplant Immunoglobulin A Nephropathy or Focal Segmental Glomerulosclerosis

Find Trials by Condition in North Carolina

Trial Investigating Visugromab in Combination With Immunochemotherapy in 1L Treatment of Participants With Metastatic NSCLC

A Randomized Trial to Assess Patient Quality of Life and Function After Alternative Surgeries for Pathologic Fractures of the Femur

RGX-314 Gene Therapy Administered in the Suprachoroidal Space for Participants With Neovascular Age-Related Macular Degeneration (nAMD)

A Study to Evaluate the Safety and Effectiveness of ALKS 2680 in Subjects With Narcolepsy Type 2

A Clinical Trial to Evaluate the Safety and Efficacy of COM701 in Relapsed Platinum Sensitive Ovarian Cancer

Mobile Health and Social Media Physical Activity Intervention Among Adolescent and Young Adult Childhood Cancer Survivors, the StepByStep Study

Progestins for the Treatment of Endometrial Cancer or Precancers of the Uterus Before Surgery, The Pro-Window Trial

Ruxolitinib vs Prednisone as First-line Therapy for cGVHD Needing Systemic Therapy

Defining Clinical Endpoints in Limb Girdle Muscular Dystrophy (LGMD)

A Clinical Trial to Assess COM503 in Participants With Advanced Solid Malignancies

A Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Anti-tumour Activity of IPN01203 in Adults With Locally Advanced or Metastatic Solid Tumours Exposed to Immune Checkpoint Inhibitor Therapies

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers

Clinical and Biomarker Effects of Depot Medroxyprogesterone Acetate in Females With Sickle Cell Disease

REFOCUS: A First-in-Human Study of Highly Selective FGFR2 Inhibitor, RLY-4008, in Patients With ICC and Other Advanced Solid Tumors

Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE Study

Rapamycin Dose-Ranging Efficacy Study in Port Wine Stains

A Study Comparing Savolitinib Plus Osimertinib vs Savolitinib Plus Placebo in Patients With EGFRm+ and MET Amplified Advanced NSCLC