Clinical Trials in New York

Showing 10781-10800 of 19,464 trials

Brodalumab in Subjects With Moderate to Severe Plaque Psoriasis Who Have Failed IL-17A Therapies

NCT03403036

This study will evaluate the safety and efficacy of brodalumab in the treatment of moderate-to-severe psoriasis in patients who have previously failed treatment with interleukin (IL)-17A therapies. Forty patients will be enrolled in this 16-week open-label study. Patients will receive 210 mg of brodalumab subcutaneous injection at weeks 0, 1, and 2, followed by 210 mg every 2 weeks. The primary efficacy endpoint will be the proportion of patients achieving a score of "0-clear" or "1-almost clear" in the sPGA score after 16 weeks of treatment. After completion of the 16-week trial, patients may desire to continue treatment with brodalumab.

Psoriasis

Icahn School of Medicine at Mount Sinai39 participantsStarted Oct 2017

New York, New York, United States • Houston, Texas, United States

COMPLETEDPhase 3< 1 mile

Adjunctive Ziprasidone in the Treatment of Bipolar I Depression

NCT00483548

The purpose of this study is to determine if a treatment regimen of ziprasidone plus a mood stabilizer is safe and effective in the short term treatment of Bipolar I Depression. Ziprasidone will be added to lithium, valproate or lamotrigine after the patient has been on a therapeutic dose of one of these mood stabilizers for at least 4 weeks.

Bipolar DisorderDepression, Bipolar

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.298 participantsStarted Oct 2007

Chandler, Arizona, United States • Litchfield Park, Arizona, United States • Little Rock, Arkansas, United States +67 more locations

Brodalumab in Subjects With Moderate to Severe Plaque Psoriasis Who Have Failed IL-17A Therapies

Adjunctive Ziprasidone in the Treatment of Bipolar I Depression

Find Trials by Condition in New York

Trial to Evaluate the Long-term Efficacy of Oral Aripiprazole in the Treatment of Pediatric Participants With Tourette's Disorder

Pivotal Study of the FRED Stent System in the Treatment of Intracranial Aneurysms

A Phase III Study to Test the Benefit of a New Kind of Anti-cancer Treatment in Patients With Melanoma, After Surgical Removal of Their Tumor

Study of Enzalutamide With and Without Sorafenib in Advanced Hepatocellular Carcinoma Patients

Celebrex vs Tramadol in the Treatment of Chronic Lower Back Pain.

A Feasibility Study to Evaluate The Effect of the Electronic Patient Visit Assessment On Pain and Quality of Life for Patients With Head and Neck Cancer (HNC)

Automated Graduated CPAP (AGPAP) for Improved Adherence in Newly Diagnosed Obstructive Sleep Apnea (OSA) Patients

Prospective Randomized Evaluation Of Celecoxib Integrated Safety Vs Ibuprofen Or Naproxen

Prevention of De Novo HCV With Antiviral HCV Therapy Post-Liver and Post-Kidney Transplant

EXPAREL Infiltrated Into the TAP for Postoperative Analgesia in Unilateral Abdominal Hernia Repair

Depsipeptide in Unresectable Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

Characterization of Proliferating Compartment in B-Cell Patients and in Healthy Aging Subjects

Late Hypothermia for Hypoxic-Ischemic Encephalopathy

Tadalafil for Pulmonary Hypertension Due to Chronic Lung Disease

CyberKnife Radiosurgical Treatment of Inoperable Early Stage Non-Small Cell Lung Cancer

CBP501, Cisplatin and Nivolumab in Advanced Refractory Tumors

Efficacy and Safety of OBE2109 in Subjects With Heavy Menstrual Bleeding Associated With Uterine Fibroids

The Nellix® EndoVascular Aneurysm Sealing System for the Treatment of Infrarenal Abdominal Aortic Aneurysms