Clinical Trials in New York

Showing 10481-10500 of 22,668 trials

A Study of Anti-CTLA-4 Antibody in Patients With Advanced Synovial Sarcoma

NCT00140855

The purpose of this study is to determine whether immune therapy with anti-CTLA-4 antibody is effective in people with advanced synovial sarcoma.

Synovial Sarcoma

Ludwig Institute for Cancer Research6 participantsStarted Jun 2005

New York, New York, United States

TERMINATEDPhase 1< 1 mile

Phase 1 Study of Tremelimumab, Durvalumab, High-dose Chemotherapy, + Autologous Stem Cell Transplant

NCT02716805

This was a Phase 1, open-label, multicenter, study of checkpoint inhibitor therapy (tremelimumab ± durvalumab) prior to and following autologous stem cell transplant (ASCT) and high-dose melphalan in subjects with multiple myeloma who were at a high risk for relapse, were eligible for ASCT, and had available cryopreserved stem cells. Primary study objectives were to determine the safety and tolerability of study treatment. Further objectives were to evaluate the clinical efficacy and biologic activity of the regimen.

Multiple Myeloma

Ludwig Institute for Cancer Research6 participantsStarted Dec 2016

New York, New York, United States • New York, New York, United States

COMPLETEDPhase 1< 1 mile

Treatment of Patients With Advanced Renal Cancer With a Radiolabeled Antibody, Yttrium-90 Conjugated Chimeric G250

NCT00199875

This was a Phase 1, open-label, dose-escalation study of yttrium-90 conjugated chimeric G250 (\^90Y-DOTA-cG250) in patients with advanced, measurable clear cell renal cell carcinoma (RCC). Study objectives were to determine the safety, targeting, and dosimetry of \^90Y-DOTA-cG250, using indium-111 conjugated chimeric G250 (\^111In-DOTA-cG250) as a surrogate, as well as to evaluate the immunogenicity of cG250.

Renal Cell CarcinomaKidney NeoplasmRenal Cancer+1 more

Ludwig Institute for Cancer Research18 participantsStarted Jul 2005

New York, New York, United States

A Study of Anti-CTLA-4 Antibody in Patients With Advanced Synovial Sarcoma

Phase 1 Study of Tremelimumab, Durvalumab, High-dose Chemotherapy, + Autologous Stem Cell Transplant

Treatment of Patients With Advanced Renal Cancer With a Radiolabeled Antibody, Yttrium-90 Conjugated Chimeric G250

Find Trials by Condition in New York

NY-ESO-1 Plasmid DNA (pPJV7611) Cancer Vaccine

A Clinical Trial of Buparlisib and Ibrutinib in Lymphoma

Phase 1/2 Study of Motolimod, Doxorubicin, and Durvalumab in Recurrent, Platinum-Resistant Ovarian Cancer

Examining Dose-Related Effects of Oxytocin on Social Cognition Across Populations

NY-ESO-1 Protein With Montanide and CpG 7909 as Cancer Vaccine in Several Tumors

A Phase I Trial of SIM1811-03 in Subjects With Advanced Solid Tumors and Cutaneous T-cell Lymphoma

Coached or Non-Coached Weight Loss Intervention

Study to Evaluate the Safety and Efficacy of High Dose Intravenous Immune Globulin (IVIG) Plus Standard Medical Treatment (SMT) Versus SMT Alone in Participants in Intensive Care Unit (ICU) With Coronavirus Disease (COVID-19)

Study To Assess The Safety And Efficacy Of The Tempsure Flexsure Applicators For Abdominal Wrinkles

Safety and Efficacy of Nerinetide (NA-1) in Subjects Undergoing Endovascular Thrombectomy for Stroke

Open-Label Safety Study of AXS-05 in Subjects With Depression

Study of Nanoliposomal Irinotecan (Nal-IRI)-Containing Regimens Versus Nab-paclitaxel Plus Gemcitabine in Patients With Previously Untreated, Metastatic Pancreatic Adenocarcinoma

Study of Abatacept in the Treatment of Hospitalized COVID-19 Participants With Respiratory Compromise

A Study to Evaluate the Efficacy and Safety of Erenumab (AMG 334) in Chronic Migraine Prevention

Study of Safety of CSJ117 in Participants With Moderate to Severe Uncontrolled Asthma

A Study of ALRN-6924 for the Prevention of Chemotherapy-induced Side Effects (Chemoprotection)

A Study to Examine Olaparib Maintenance Retreatment in Patients With Epithelial Ovarian Cancer.