Clinical Trials in New York

Showing 6561-6580 of 22,668 trials

Efficacy and Safety Study of Narsoplimab in Pediatric Patients With High-Risk Hematopoietic Stem Cell Transplant TMA

NCT05855083

The purpose of this study is to evaluate the safety and efficacy of narsoplimab in pediatric patients with thrombotic microangiopathies (TMA) following hematopoietic stem cell transplant (HSCT).

Thrombotic MicroangiopathiesHematopoietic Stem Cell Transplantation

Omeros Corporation18 participantsStarted May 2023

San Diego, California, United States • Gainesville, Florida, United States • Boston, Massachusetts, United States +13 more locations

RECRUITING< 1 mile

Special Care Patterns for Elderly HNSCC Patients Undergoing Radiotherapy

NCT05337631

The number of elderly head-and-neck squamous cell carcinoma (HNSCC) patients is increasing; however, the evidence regarding the ideal treatment for this often vulnerable and frail patient cohort is limited. Although the benefit of concomitant chemotherapy has been reported to decrease in elderly HNSCC patients based on the MACH-NC meta-analysis, it remains unknown whether state-of-the art radiotherapy techniques such as intensity-modulated radiotherapy (IMRT), modern supportive treatments and alternative chemotherapy fractionation (e.g., cisplatin weekly) may have altered this observation. The objective of this retrospective multinational multicenter study is to determine the oncological outcomes of elderly patients (≥65 years) with locally advanced HNSCCs undergoing definitive (chemo-)radiation and to investigate the influence of concomitant chemotherapy on overall survival and progression-free survival after adjusting for potential confounder variables such as age, performance status and comorbidity burden.

HNSCCOral Cavity CancerOropharynx Cancer+2 more

University Hospital Freiburg1,500 participantsStarted Jun 2021

Baltimore, Maryland, United States • New York, New York, United States • Cleveland, Ohio, United States +15 more locations

Efficacy and Safety Study of Narsoplimab in Pediatric Patients With High-Risk Hematopoietic Stem Cell Transplant TMA

Special Care Patterns for Elderly HNSCC Patients Undergoing Radiotherapy

Find Trials by Condition in New York

Efficacy Against Oral Persistent Infection, Immunogenicity and Safety of the 9-valent Human Papillomavirus Vaccine (9vHPV) in Men Aged 20-45 Years (V503-049)

A Phase 3 Clinical Trial of CCX168 (Avacopan) in Patients With ANCA-Associated Vasculitis

ALTTO (Adjuvant Lapatinib And/Or Trastuzumab Treatment Optimisation) Study; BIG 2-06/N063D

A Study to Evaluate the Efficacy and Safety of Sutetinib Maleate Capsule in Locally Advanced or Metastatic NSCLC

4D-125 in Patients With X-Linked Retinitis Pigmentosa (XLRP)

PLX3397 Plus Sirolimus in Unresectable Sarcoma and Malignant Peripheral Nerve Sheath Tumors

NOVOCART®3D for Treatment of Articular Cartilage of the Knee

Safety, Pharmacokinetics and Efficacy of Paxalisib (GDC-0084) in Newly-diagnosed Glioblastoma

Heart Failure Optimization Study

Enhancing Reading Recovery in Aphasia With tDCS and Phonomotor Therapy

A Study to Evaluate the Efficacy and Safety of OTX-TIC (Travoprost) Intracameral Implant for Patients With Open-angle Glaucoma (OAG) or Ocular Hypertension (OHT)

A Prospective Observational Study of TPIAT

BURAN: Benralizumab on Airway Dynamics in Severe Eosinophilic Asthma Using Functional Respiratory Imaging

Effect of Fetal Aortic Valvuloplasty on Outcomes

A Study to Evaluate the Efficacy and Safety of Nanosomal Docetaxel Lipid Suspension in Triple Negative Breast Cancer Patients

NOVOCART 3D Treatment Following Microfracture Failure

First-in-human Single Agent Study of SAR442257 in RRMM and RR-NHL

Study to Investigate Hepatic Impairment on PK, Safety, Tolerability of Camizestrant in Post-Menopausal Female Subjects