Clinical Trials in New York

Showing 6101-6120 of 17,259 trials

Comparative Effectiveness of Biologics or Small Molecule Therapies in Inflammatory Bowel Disease (IBD)

NCT04852666

The purpose of this study is to assess effectiveness of vedolizumab versus ustekinumab in patients with Crohn's disease and vedolizumab versus tofacitinib in patients with ulcerative colitis, after non-response to anti-tumor necrosis factor (TNF) medications, using data from two existing cohorts.

Crohn's DiseaseUlcerative Colitis

University of North Carolina, Chapel Hill465 participantsStarted Jul 2019

New York, New York, United States • Chapel Hill, North Carolina, United States

COMPLETEDPhase 1/2< 1 mile

Isatuximab in Combination With Cemiplimab in Relapsed/Refractory Multiple Myeloma (RRMM) Patients

NCT03194867

Primary Objectives: * To evaluate the safety and tolerability of the combination of isatuximab (also known as SAR650984) and cemiplimab (also known as REGN2810) in patients with relapse/refractory multiple myeloma. * To compare the overall response of the combination of isatuximab and cemiplimab versus isatuximab alone in patients with RRMM based on International Myeloma Working Group (IMWG) criteria. Secondary Objectives: * To evaluate the efficacy as assessed by clinical benefit rate (CBR), duration of response (DOR), time to response (TTR), progression free survival (PFS), and overall survival (OS). * To assess the pharmacokinetics (PK) of isatuximab and cemiplimab when given in combination. * To assess the immunogenicity of isatuximab and cemiplimab when given in combination.

Plasma Cell Myeloma

Sanofi109 participantsStarted Feb 2018

Denver, Colorado, United States • Kansas City, Kansas, United States • New York, New York, United States +27 more locations

Comparative Effectiveness of Biologics or Small Molecule Therapies in Inflammatory Bowel Disease (IBD)

Isatuximab in Combination With Cemiplimab in Relapsed/Refractory Multiple Myeloma (RRMM) Patients

Find Trials by Condition in New York

Abaloparatide and Pelvic Fracture Healing

Utility of Ultrasound Assessment of the Inferior Vena Cava in Patients With Sepsis and Dehydration

Tradipitant in Treatment-resistant Pruritus Associated With Atopic Dermatitis

A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Miricorilant in Obese Adult Patients With Schizophrenia While Taking Antipsychotic Medications (GRATITUDE II)

Study of TPX-0046, A RET/SRC Inhibitor in Adult Subjects With Advanced Solid Tumors Harboring RET Fusions or Mutations

A Study to Evaluate LB1148 for Return of Bowel Function in Subjects Undergoing Bowel Resection

Neuroimaging of Donor Iron Deficient Study

HB-302/HB-301 Therapy in Participants With Metastatic Castration-Resistant Prostate Cancer

Bridge to HOPE: Hypothermic Oxygenated Perfusion Versus Cold Storage Prior to Liver Transplantation

A Study to Examine the Efficacy and Safety of Anti-Fel d 1 Antibodies Injections in Cat-allergic Adolescent and Adult Patients With Allergic Rhinitis Who Live With a Cat

Long-Term Safety of ARQ-154 Foam in Subjects With Seborrheic Dermatitis

Epacadostat and Pembrolizumab in Patients With GIST

Phase I Study of Cell Therapies for the Treatment of Patients With Relapsed or Refractory AML or High-risk MDS

Study of ADCT-301 in Patients With Selected Advanced Solid Tumors

A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

Category Learning Retention in Adults With and Without Developmental Language Disorder

Investigating Gains in Neurocognition in an Intervention Trial of Exercise

A Study of TAK-981 Given With Rituximab in Adults With Relapsed or Refractory CD20-Positive Non-Hodgkin Lymphoma