Clinical Trials in New York

Showing 4661-4680 of 17,259 trials

Chronic Pain in Rheumatoid Arthritis

NCT05038553

The objective is to identify modifiable clinical factors and neurobiological pathways that lead to the development of chronic pain in patients with early rheumatoid arthritis. Participants will undergo quantitative sensory testing, a type of testing that involves assessing response to well-defined, quantifiable painful stimuli, at 0, 3, and 12 months. A subset of participants will also undergo magnetic resonance imaging at 0 and 12 months to assess neuroimaging markers that have previously been shown to be involved in chronic pain.

Arthritis, RheumatoidPain

Northwestern University125 participantsStarted Oct 2021

Denver, Colorado, United States • Chicago, Illinois, United States • Baltimore, Maryland, United States +2 more locations

COMPLETEDPhase 2< 1 mile

A Study to Evaluate the Safety and Efficacy of Intranasal Esketamine in Treatment-resistant Depression

NCT01998958

The purpose of this study is to assess the efficacy and dose response of intranasal esketamine (Panel A: 28 mg, 56 mg, and 84 mg and Panel B: 14 mg and 56 mg) compared with placebo in improving depressive symptoms in participants with treatment-resistant depression (TRD).

Treatment Resistant Depressive Disorder

Janssen Research & Development, LLC108 participantsStarted Jan 2014

Birmingham, Alabama, United States • Garden Grove, California, United States • Hartford, Connecticut, United States +22 more locations

Chronic Pain in Rheumatoid Arthritis

A Study to Evaluate the Safety and Efficacy of Intranasal Esketamine in Treatment-resistant Depression

Find Trials by Condition in New York

Genetic Studies of Early-onset Dementia

A Study to Evaluate the Efficacy and Safety of JNJ-42847922 as Adjunctive Therapy to Antidepressants in Adult Participants With Major Depressive Disorder Who Have Responded Inadequately to Antidepressant Therapy

A Study of Ustekinumab in Participants With Active Systemic Lupus Erythematosus

A Study of Carfilzomib, Lenalidomide, Dexamethasone and Daratumumab for Patients With Relapsed/Refractory Myeloma With Salvage Autologous Hematopoietic Cell Transplantation

Nivolumab and BMS-986253 for Hormone-Sensitive Prostate Cancer (MAGIC-8)

APX005M and Doxorubicin in Advanced Sarcoma

An Efficacy and Safety Study of Sirukumab in Participants With Major Depressive Disorder

A Long-term, Safety and Efficacy Study of Intranasal Esketamine in Treatment-resistant Depression

A Study to Assess the Effect of Seltorexant Compared to Placebo on Respiration During Sleep in Adult Participants With Obstructive Sleep Apnea

The Celljuvant Study: A Phase 3 Immunogenicity and Safety Study of aQIVc Vaccine in Adults Aged 50 Years and Older

A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant and Long-term Safety Extension Treatment With Seltorexant

Open-Label Extension: Tolerability and Effects of ALK-001 on Stargardt Disease (TEASE)

A Study of Severe Uterine Bleeding Following Exposure to Direct Oral Anticoagulants

A Study of Comparing Rates of Dementia and Alzheimer's Disease in Participants Initiating Methotrexate Versus Those Initiating Anti-tumor Necrosis Factor (TNF)-Alpha Therapy

A Study of Suboptimally Controlled Participants Previously Taking Injectable DMDs for RMS (CLICK-MS)

Safety, Tolerability and Efficacy of ACZ885 on Leg Artery Structure in Patients With Peripheral Artery Disease

A Phase 1/2, First-in-Human Dose Escalation/Expansion Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of a Subretinal Injection of SB-007 in Subjects With Stargardt Disease (STGD1)

Study of Dabrafenib+Trametinib in the Adjuvant Treatment of Stage III BRAF V600+ Melanoma After Complete Resection to Evaluate the Impact on Pyrexia Related Outcomes