Clinical Trials in New York

Showing 22521-22540 of 22,668 trials

A Study of Letrazuril in the Treatment of AIDS-Related Diarrhea

NCT00001018

To determine the pharmacokinetic profile of single doses of letrazuril in patients with AIDS-related cryptosporidial diarrhea; to determine the dose proportionality of single escalating doses of letrazuril; to determine steady-state concentrations of letrazuril; to evaluate the safety and efficacy of escalating doses of letrazuril, compared with placebo, for patients with AIDS-related cryptosporidial diarrhea. Letrazuril, the p-fluor analog of diclazuril, has been shown in an animal model to prevent infections by organisms closely related to the intracellular parasite Cryptosporidium. Reliable data are needed to show the effectiveness of letrazuril in treating AIDS-related cryptosporidial diarrhea.

CryptosporidiosisHIV Infections

National Institute of Allergy and Infectious Diseases (NIAID)32 participants

Los Angeles, California, United States • New York, New York, United States • New York, New York, United States +1 more locations

COMPLETEDPhase 2< 1 mile

Phase II Study of Midodrine for Neurogenic Orthostatic Hypotension

NCT00004268

OBJECTIVES: I. Study further the safety and efficacy of the alpha-receptor agonist midodrine in patients with neurogenic orthostatic hypotension. II. Assess the quality of life in these patients with this treatment regimen.

Orthostatic Hypotension

National Center for Research Resources (NCRR)300 participantsStarted Apr 2001

New York, New York, United States

UNKNOWN< 1 mile

The Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study

NCT00000155

To describe the clinical course of keratoconus and to describe the relationships among its visual and physiological manifestations, including high- and low-contrast visual acuity, corneal curvature, slit lamp biomicroscopic findings, corneal scarring, and quality of life. To identify risk factors and protective factors that influence the severity and progression of keratoconus.

Keratoconus

National Eye Institute (NEI)Started Jun 1995

Berkeley, California, United States • Fullerton, California, United States • Los Angeles, California, United States +11 more locations

A Study of Letrazuril in the Treatment of AIDS-Related Diarrhea

Phase II Study of Midodrine for Neurogenic Orthostatic Hypotension

The Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study

Find Trials by Condition in New York

Evaluating the Effectiveness of a Dichloroacetate in MELAS Syndrome

A Randomized Phase II Efficacy, Activity and Safety Study of GLQ223 Alone and in Combination With Zidovudine in Symptomatic HIV-Infected Patients Without Prior Treatment With GLQ223 or Trichosanthin

The Safety and Effectiveness of Lamivudine Plus Zidovudine, Used With and Without 1592U89, in HIV-1 Infected Patients Who Have Never Taken Anti-HIV Drugs

A Study of T-20 in HIV-Positive Adults

A Randomized Controlled Study of the Efficacy and Safety of Maintenance Treatment With Oral Ganciclovir for Newly Diagnosed Cytomegalovirus Retinitis in People With AIDS

A Study to Access the Safety/Efficacy of Thalidomide in the Treatment of Anemia in Patients With Myelodysplastic Syndromes

Comparing Side Effects of Two Forms of Videx in HIV-Infected Adults

A Study to Compare Two Anti-HIV Drug Combinations

A Study of Different Doses of Atevirdine Mesylate Plus Zidovudine in HIV-Positive Patients

Safety and Effectiveness of Giving L-743,872 to Patients With Thrush That Has Not Been Cured With Fluconazole

A Double-Blind, Placebo-Controlled Study With Open-Label Follow-Up To Determine the Safety and Efficacy of r-HuEPO in AIDS and Advanced ARC Patients With Anemia

A Double-Blind, Placebo-Controlled Study With Open-Label Follow-Up To Determine the Safety and Efficacy of r-HuEPO in AIDS Patients With Anemia Induced by Their Disease and AZT Therapy

A Double-Blind, Placebo-Controlled Study With Open-Label Follow-Up To Determine the Safety and Efficacy of Subcutaneous Doses of r-HuEPO in AIDS Patients With Anemia Induced by Their Disease and AZT Therapy

A Double-Blind Study to Evaluate the Safety and Pharmacokinetics of L-Ofloxacin (RWJ 25213) in Subjects With HIV Infection

A Study of L-735,524 in HIV-Positive Children and Adolescents

The Safety of Tenofovir Disoproxil Fumarate Taken With Other Anti-HIV Drugs to Treat HIV-Infected Patients

Randomized Study of Decreased Hyperinsulinemia on the Ovulatory Response to Clomiphene Citrate in Women With Polycystic Ovary Syndrome